Timolol Impurity E

Name: Timolol Impurity E
Brand: Vaqora Chemicals
SKU: VQ-028395

About Timolol Impurity E

Timolol Impurity E is an impurity of Timolol carrying the CAS registry number 1026075-53-5. With the molecular formula C17H26N4O6S, it has a molar mass of 414.5 g/mol. It is also known as Timolol EP Impurity E or Timolol Maleate - Impurity E.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Timolol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Timolol Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Timolol

View every impurity, metabolite and intermediate we list for Timolol.

Timolol impurities

Specifications & identifiers

Chemical identifiers
Product name	Timolol Impurity E
Catalogue No.	VQ-028395
CAS Number	1026075-53-5
IUPAC name	(Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid
Molecular formula	C₁₇H₂₆N₄O₆S
Molecular weight	414.5 g/mol
Exact mass	414.1573
Grade	Reference Standard
HSN code	38229090
InChIKey	MGIAXRFZDNBKRF-RXNFCKPNSA-N
SMILES	CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)OC(=O)/C=C\C(=O)O
PubChem CID	10112466

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	2 / 11
TPSA	151 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Timolol Impurity E?

The CAS Registry Number of Timolol Impurity E is 1026075-53-5. It is also known as Timolol EP Impurity E, Timolol Maleate - Impurity E, Timolol maleate ester.

What is the molecular formula and molecular weight of Timolol Impurity E?

Timolol Impurity E has the molecular formula C17H26N4O6S and a molecular weight of 414.5 g/mol. Its IUPAC name is (Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid.

What is Timolol Impurity E used for?

Timolol Impurity E is supplied as a characterised reference material related to Timolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Timolol Impurity E can I order?

We supply Timolol Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Timolol Impurity E?

Yes. Every lot of Timolol Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Timolol Impurity E be shipped internationally?

Yes. Timolol Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.