Treosulfan

Name: Treosulfan
Brand: Vaqora Chemicals
SKU: VQ-034413

About Treosulfan

Treosulfan is a high-purity reference standard of Treosulfan carrying the CAS registry number 299-75-2. Its molecular formula is C6H14O8S2 and its molecular weight is 278.3 g/mol. The IUPAC name is [(2S,3S)-2,3-dihydroxy-4-methylsulfonyloxybutyl] methanesulfonate. It is also known as L-Threitol 1,4-dimethanesulfonate or (2S,3S)-Threitol 1,4-bismethanesulfonate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Treosulfan standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Treosulfan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Treosulfan

View every impurity, metabolite and intermediate we list for Treosulfan.

Treosulfan impurities

Specifications & identifiers

Chemical identifiers
Product name	Treosulfan
Catalogue No.	VQ-034413
CAS Number	299-75-2
IUPAC name	[(2S,3S)-2,3-dihydroxy-4-methylsulfonyloxybutyl] methanesulfonate
Molecular formula	C₆H₁₄O₈S₂
Molecular weight	278.3 g/mol
Exact mass	278.013
Grade	Reference Standard
HSN code	38229090
InChIKey	YCPOZVAOBBQLRI-WDSKDSINSA-N
SMILES	CS(=O)(=O)OC[C@@H]([C@H](COS(=O)(=O)C)O)O
PubChem CID	9882105

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.2
H-bond donors / acceptors	2 / 8
TPSA	144 Å²
Synonyms	L-Threitol 1,4-dimethanesulfonate, (2S,3S)-Threitol 1,4-bismethanesulfonate, L-Threityl dimesylate, L-Threitol, 1,4-bis(methanesulfonate), L-dihydroxybusulfan, Threitol, 1,4-dimethanesulfonate, (2S,3S)-, (S-(R,R))-1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, (2S,3S)-2,3-dihydroxy-4-(methanesulfonyloxy)butyl methanesulfonate, L-threitol-1,4-bismethanesulfonate, Threitol, 1,4-dimethanesulfonate, (2,3-dihydroxy-4-methylsulfonyloxybutyl) methanesulfonate, (S-(R,R))-1,2,3,4-butanetetrol,1,4-dimethanesulfonate

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H340May cause genetic defects
H350May cause cancer
H371May cause damage to organs

Precautionary statements: P203, P260, P264, P270, P280, P308 + P316, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Treosulfan?

The CAS Registry Number of Treosulfan is 299-75-2. It is also known as L-Threitol 1,4-dimethanesulfonate, (2S,3S)-Threitol 1,4-bismethanesulfonate, L-Threityl dimesylate.

What is the molecular formula and molecular weight of Treosulfan?

Treosulfan has the molecular formula C6H14O8S2 and a molecular weight of 278.3 g/mol. Its IUPAC name is [(2S,3S)-2,3-dihydroxy-4-methylsulfonyloxybutyl] methanesulfonate.

What is Treosulfan used for?

Treosulfan is supplied as a characterised reference material related to Treosulfan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Treosulfan can I order?

We supply Treosulfan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Treosulfan?

Yes. Every lot of Treosulfan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Treosulfan be shipped internationally?

Yes. Treosulfan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.