Trientine Tetrahydrochloride

Name: Trientine Tetrahydrochloride
Brand: Vaqora Chemicals
SKU: VQ-034429

About Trientine Tetrahydrochloride

Vaqora Chemicals supplies Trientine Tetrahydrochloride, an impurity of Trientine registered under CAS number 4961-40-4. With the molecular formula C6H22Cl4N4, it has a molar mass of 292.1 g/mol. It is also known as Triethylenetetramine Tetrahydrochloride or Trientine Tetrahydrochloride form B.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Trientine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Trientine Tetrahydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Trientine

View every impurity, metabolite and intermediate we list for Trientine.

Trientine impurities

Specifications & identifiers

Chemical identifiers
Product name	Trientine Tetrahydrochloride
Catalogue No.	VQ-034429
CAS Number	4961-40-4
IUPAC name	N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;tetrahydrochloride
Molecular formula	C₆H₂₂Cl₄N₄
Molecular weight	292.1 g/mol
Exact mass	292.0569
Grade	Reference Standard
HSN code	38229090
InChIKey	OKHMDSCYUWAQPT-UHFFFAOYSA-N
SMILES	C(CNCCNCCN)N.Cl.Cl.Cl.Cl
PubChem CID	71434

Physical properties
Physical form	Solid
H-bond donors / acceptors	8 / 4
TPSA	76.1 Å²
Synonyms	Triethylenetetramine Tetrahydrochloride, Triethylenetetramine tetrahydrochloride (1st FRG), Trientine Tetrahydrochloride form B, Triethylenetetramine, tetrahydrochloride, 1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-, tetrahydrochloride, N,N'-Bis(2-aminoethyl)-1,2-ethanediamine tetrahydrochloride, TETA 4HCl, N1,N1-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) tetrahydrochloride, N1,N1'-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) tetrahydrochloride, Trientine tetrahydrochloride (USAN), 1,2-Ethanediamine, N1,N2-bis(2-aminoethyl)-, hydrochloride (1:4), 3,6-Diazaoctane-1,8-diamine tetrahydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trientine Tetrahydrochloride?

The CAS Registry Number of Trientine Tetrahydrochloride is 4961-40-4. It is also known as Triethylenetetramine Tetrahydrochloride, Triethylenetetramine tetrahydrochloride (1st FRG), Trientine Tetrahydrochloride form B.

What is the molecular formula and molecular weight of Trientine Tetrahydrochloride?

Trientine Tetrahydrochloride has the molecular formula C6H22Cl4N4 and a molecular weight of 292.1 g/mol.

What is Trientine Tetrahydrochloride used for?

Trientine Tetrahydrochloride is supplied as a characterised reference material related to Trientine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trientine Tetrahydrochloride can I order?

We supply Trientine Tetrahydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trientine Tetrahydrochloride?

Yes. Every lot of Trientine Tetrahydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trientine Tetrahydrochloride be shipped internationally?

Yes. Trientine Tetrahydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.