Triethoxymethyl)benzene

Name: Triethoxymethyl)benzene
Brand: Vaqora Chemicals
SKU: VQ-049253

About Triethoxymethyl)benzene

Triethoxymethyl)benzene is a process intermediate or related compound of Nintedanib carrying the CAS registry number 1663-61-2. Formula C13H20O3, molecular weight 224.3 g/mol. Alternative names: Triethyl orthobenzoate and Benzene, (triethoxymethyl)-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Nintedanib, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Triethoxymethyl)benzene in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Triethoxymethyl)benzene
Catalogue No.	VQ-049253
CAS Number	1663-61-2
IUPAC name	triethoxymethylbenzene
Molecular formula	C₁₃H₂₀O₃
Molecular weight	224.3 g/mol
Exact mass	224.1412
InChIKey	BQFPCTXLBRVFJL-UHFFFAOYSA-N
SMILES	CCOC(C1=CC=CC=C1)(OCC)OCC
PubChem CID	74268

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	0 / 3
TPSA	27.7 Å²
Synonyms	Triethyl orthobenzoate, Benzene, (triethoxymethyl)-, Ethyl orthobenzoate, Orthobenzoic acid, triethyl ester, Orthobenzoic Acid Triethyl Ester, Triethylorthobenzoate, alpha,alpha,alpha-Triethoxytoluene

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Triethoxymethyl)benzene?

The CAS Registry Number of Triethoxymethyl)benzene is 1663-61-2. It is also known as Triethyl orthobenzoate, Benzene, (triethoxymethyl)-, Ethyl orthobenzoate.

What is the molecular formula and molecular weight of Triethoxymethyl)benzene?

Triethoxymethyl)benzene has the molecular formula C13H20O3 and a molecular weight of 224.3 g/mol. Its IUPAC name is triethoxymethylbenzene.

What is Triethoxymethyl)benzene used for?

Triethoxymethyl)benzene is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Triethoxymethyl)benzene can I order?

We supply Triethoxymethyl)benzene, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Triethoxymethyl)benzene?

Yes. Every lot of Triethoxymethyl)benzene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Triethoxymethyl)benzene be shipped internationally?

Yes. Triethoxymethyl)benzene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.