Triethyl (2E)-3-Methyl-4-phosphonocrotonate

Name: Triethyl (2E)-3-Methyl-4-phosphonocrotonate
Brand: Vaqora Chemicals
SKU: VQ-031294

About Triethyl (2E)-3-Methyl-4-phosphonocrotonate

Listed under CAS 39760-56-0, Triethyl (2E)-3-Methyl-4-phosphonocrotonate is an impurity of Isotretinoin available from Vaqora Chemicals. With the molecular formula C11H21O5P, it has a molar mass of 264.25 g/mol. The IUPAC name is ethyl (E)-4-diethoxyphosphoryl-3-methylbut-2-enoate. Common synonyms include Triethyl 3-Methyl-4-phosphonocrotonate and Triethyl 3-methyl-4-phosphono-2-butenoate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Isotretinoin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Triethyl (2E)-3-Methyl-4-phosphonocrotonate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	Triethyl (2E)-3-Methyl-4-phosphonocrotonate
Catalogue No.	VQ-031294
CAS Number	39760-56-0
IUPAC name	ethyl (E)-4-diethoxyphosphoryl-3-methylbut-2-enoate
Molecular formula	C₁₁H₂₁O₅P
Molecular weight	264.25 g/mol
Exact mass	264.1127
Grade	Reference Standard
HSN code	38229090
InChIKey	OQKGPUSERILONW-CSKARUKUSA-N
SMILES	CCOC(=O)/C=C(\C)/CP(=O)(OCC)OCC
PubChem CID	6000084

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	0 / 5
TPSA	61.8 Å²
Synonyms	Triethyl 3-Methyl-4-phosphonocrotonate, Ethyl 4-(diethoxyphosphoryl)-3-methylbut-2-enoate, Triethyl 3-methyl-4-phosphono-2-butenoate, (E)-ethyl 4-(diethoxyphosphoryl)-3-methylbut-2-enoate, (Z)-3-Methyl-4-phosphono-crotonic Acid Triethyl Ester, Triethyl 3-Methyl-4-phosphono-2-butenoate (~90per cent), Triethyl 4-phosphono-3-methyl-2-butenoate, Triethyl 4-phosphonosenecioate, (E)-4-(Diethoxy-phosphoryl)-3-methyl-but-2-enoic acid ethyl ester, diethyl 3-ethoxycarbonyl-2-methyl-2-propenylphosphonate, Triethyl 3-methyl-4-phosphono-2-butenoate, mixture of cis and trans, ethyl 4(diethoxyphosphoryl)-3-methyl-but-2E-enoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Triethyl (2E)-3-Methyl-4-phosphonocrotonate?

The CAS Registry Number of Triethyl (2E)-3-Methyl-4-phosphonocrotonate is 39760-56-0. It is also known as Triethyl 3-Methyl-4-phosphonocrotonate, Ethyl 4-(diethoxyphosphoryl)-3-methylbut-2-enoate, Triethyl 3-methyl-4-phosphono-2-butenoate.

What is the molecular formula and molecular weight of Triethyl (2E)-3-Methyl-4-phosphonocrotonate?

Triethyl (2E)-3-Methyl-4-phosphonocrotonate has the molecular formula C11H21O5P and a molecular weight of 264.25 g/mol. Its IUPAC name is ethyl (E)-4-diethoxyphosphoryl-3-methylbut-2-enoate.

What is Triethyl (2E)-3-Methyl-4-phosphonocrotonate used for?

Triethyl (2E)-3-Methyl-4-phosphonocrotonate is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Triethyl (2E)-3-Methyl-4-phosphonocrotonate can I order?

We supply Triethyl (2E)-3-Methyl-4-phosphonocrotonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Triethyl (2E)-3-Methyl-4-phosphonocrotonate?

Yes. Every lot of Triethyl (2E)-3-Methyl-4-phosphonocrotonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Triethyl (2E)-3-Methyl-4-phosphonocrotonate be shipped internationally?

Yes. We export Triethyl (2E)-3-Methyl-4-phosphonocrotonate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.