Varenicline Nitroso Impurity 1

Name: Varenicline Nitroso Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-007064

About Varenicline Nitroso Impurity 1

Vaqora Chemicals supplies Varenicline Nitroso Impurity 1, a nitrosamine impurity of Varenicline registered under CAS number 2755871-02-2. Its molecular formula is C13H12N4O and its molecular weight is 240.26 g/mol. The IUPAC name is 14-nitroso-5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene. Alternative names: N-Nitroso Varenicline and N-nitroso-varenicline.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Varenicline, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Varenicline Nitroso Impurity 1 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Varenicline

View every impurity, metabolite and intermediate we list for Varenicline.

Varenicline impurities

Specifications & identifiers

Chemical identifiers
Product name	Varenicline Nitroso Impurity 1
Catalogue No.	VQ-007064
CAS Number	2755871-02-2
IUPAC name	14-nitroso-5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene
Molecular formula	C₁₃H₁₂N₄O
Molecular weight	240.26 g/mol
Exact mass	240.1011
Grade	Reference Standard
HSN code	38229090
InChIKey	PTBAEGOZXFWTJH-UHFFFAOYSA-N
SMILES	C1C2CN(CC1C3=CC4=NC=CN=C4C=C23)N=O
PubChem CID	163880833

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	0 / 5
TPSA	58.5 Å²
Synonyms	8-Nitroso-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline, N-Nitroso Varenicline, N-nitroso-varenicline, 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-nitroso-, Varenicline Nitrosamine (N-nitrosovarenicline)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H351Suspected of causing cancer
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P264, P270, P273, P280, P301 + P317, P318, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Varenicline Nitroso Impurity 1?

The CAS Registry Number of Varenicline Nitroso Impurity 1 is 2755871-02-2. It is also known as 8-Nitroso-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline, N-Nitroso Varenicline, N-nitroso-varenicline.

What is the molecular formula and molecular weight of Varenicline Nitroso Impurity 1?

Varenicline Nitroso Impurity 1 has the molecular formula C13H12N4O and a molecular weight of 240.26 g/mol. Its IUPAC name is 14-nitroso-5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene.

What is Varenicline Nitroso Impurity 1 used for?

Varenicline Nitroso Impurity 1 is supplied as a characterised reference material related to Varenicline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Varenicline Nitroso Impurity 1 can I order?

We supply Varenicline Nitroso Impurity 1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Varenicline Nitroso Impurity 1?

Yes. Every lot of Varenicline Nitroso Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Varenicline Nitroso Impurity 1 be shipped internationally?

Yes. Varenicline Nitroso Impurity 1 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.