Voclosporin

Name: Voclosporin
Brand: Vaqora Chemicals
SKU: VQ-034671

About Voclosporin

Listed under CAS 515814-01-4, Voclosporin is a high-purity reference standard of Voclosporin available from Vaqora Chemicals. The compound has the formula C63H111N11O12, corresponding to a molecular weight of 1214.6 g/mol. Alternative names: ISAtx-247 and ISA-247.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Voclosporin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Voclosporin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Voclosporin

View every impurity, metabolite and intermediate we list for Voclosporin.

Voclosporin impurities

Specifications & identifiers

Chemical identifiers
Product name	Voclosporin
Catalogue No.	VQ-034671
CAS Number	515814-01-4
IUPAC name	(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhepta-4,6-dienyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular formula	C₆₃H₁₁₁N₁₁O₁₂
Molecular weight	1214.6 g/mol
Exact mass	1213.8414
Grade	Reference Standard
HSN code	38229090
InChIKey	BICRTLVBTLFLRD-PTWUADNWSA-N
SMILES	CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C=C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
PubChem CID	6918486

Physical properties
Physical form	Solid
LogP (XLogP3)	7.9
H-bond donors / acceptors	5 / 12
TPSA	279 Å²
Synonyms	ISAtx-247, ISA-247, Voclosporine, LX-211, ISA(TX)247, Vaclosporine, ISATX 247, 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A, trans-ISA 247, ISA 247, trans-ISA-247, 3odi

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Voclosporin?

The CAS Registry Number of Voclosporin is 515814-01-4. It is also known as ISAtx-247, ISA-247, Voclosporine.

What is the molecular formula and molecular weight of Voclosporin?

Voclosporin has the molecular formula C63H111N11O12 and a molecular weight of 1214.6 g/mol.

What is Voclosporin used for?

Voclosporin is supplied as a characterised reference material related to Voclosporin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Voclosporin can I order?

We supply Voclosporin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Voclosporin?

Yes. Every lot of Voclosporin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Voclosporin be shipped internationally?

Yes. Voclosporin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.