Vonoprazan

Name: Vonoprazan
Brand: Vaqora Chemicals
SKU: VQ-007852

About Vonoprazan

Vonoprazan is a high-purity reference standard of Vonoprazan carrying the CAS registry number 881681-00-1. The compound has the formula C17H16FN3O2S, corresponding to a molecular weight of 345.4 g/mol. Its systematic (IUPAC) name is 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine. Common synonyms include TAK 438 (free form) and TAK-438 free base.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Vonoprazan standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Vonoprazan

View every impurity, metabolite and intermediate we list for Vonoprazan.

Vonoprazan impurities

Specifications & identifiers

Chemical identifiers
Product name	Vonoprazan
Catalogue No.	VQ-007852
CAS Number	881681-00-1
Other CAS	881681-01-2, 1957202-44-6
IUPAC name	1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine
Molecular formula	C₁₇H₁₆FN₃O₂S
Molecular weight	345.4 g/mol
Exact mass	345.0947
Grade	Reference Standard
HSN code	38229090
InChIKey	BFDBKMOZYNOTPK-UHFFFAOYSA-N
SMILES	CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3
PubChem CID	15981397

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 5
TPSA	72.4 Å²
Synonyms	5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine, 1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine, TAK 438 (free form), 1-(5-(2-Fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine, 1H-pyrrole-3-methanamine, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-, {[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]methyl}(methyl)amine, ((5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl)methyl)(methyl)amine, 1-(5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl)-N-methylmethanamine, 1-[5-(2-Fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine, TAK-438 free base, 1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine, Vonoprazan free base

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Vonoprazan?

The CAS Registry Number of Vonoprazan is 881681-00-1. It is also known as 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine, 1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine, TAK 438 (free form).

What is the molecular formula and molecular weight of Vonoprazan?

Vonoprazan has the molecular formula C17H16FN3O2S and a molecular weight of 345.4 g/mol. Its IUPAC name is 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine.

What is Vonoprazan used for?

Vonoprazan is supplied as a characterised reference material related to Vonoprazan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Vonoprazan can I order?

We supply Vonoprazan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Vonoprazan?

Yes. Every lot of Vonoprazan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Vonoprazan be shipped internationally?

Yes. We export Vonoprazan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.