Voxelotor Impurity 1

Name: Voxelotor Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-042955

About Voxelotor Impurity 1

Listed under CAS 1282518-60-8, Voxelotor Impurity 1 is an impurity of Voxelotor available from Vaqora Chemicals. The compound has the formula C12H21BN2O2, corresponding to a molecular weight of 236.12 g/mol. The IUPAC name is 1-propan-2-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Voxelotor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Voxelotor

View every impurity, metabolite and intermediate we list for Voxelotor.

Voxelotor impurities

Specifications & identifiers

Chemical identifiers
Product name	Voxelotor Impurity 1
Catalogue No.	VQ-042955
CAS Number	1282518-60-8
IUPAC name	1-propan-2-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
Molecular formula	C₁₂H₂₁BN₂O₂
Molecular weight	236.12 g/mol
Exact mass	236.1696
Grade	Reference Standard
HSN code	38229090
InChIKey	ZKZJXVGTTZXHGX-UHFFFAOYSA-N
SMILES	B1(OC(C(O1)(C)C)(C)C)C2=CC=NN2C(C)C
PubChem CID	56776710

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 3
TPSA	36.3 Å²
Synonyms	1-(Propan-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-Isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-(propan-2-yl)-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-Isopropyl-1H-pyrazole-5-boronic acid pinacol ester, 1H-Pyrazole, 1-(1-methylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1-(1-Methylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-Isopropyl-5-(4455-tetramethyl-132-dioxaborolan-2-yl)-1H-pyrazole

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Voxelotor Impurity 1?

The CAS Registry Number of Voxelotor Impurity 1 is 1282518-60-8. It is also known as 1-(Propan-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-Isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-(propan-2-yl)-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole.

What is the molecular formula and molecular weight of Voxelotor Impurity 1?

Voxelotor Impurity 1 has the molecular formula C12H21BN2O2 and a molecular weight of 236.12 g/mol. Its IUPAC name is 1-propan-2-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole.

What is Voxelotor Impurity 1 used for?

Voxelotor Impurity 1 is supplied as a characterised reference material related to Voxelotor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Voxelotor Impurity 1 can I order?

We supply Voxelotor Impurity 1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Voxelotor Impurity 1?

Yes. Every lot of Voxelotor Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Voxelotor Impurity 1 be shipped internationally?

Yes. Voxelotor Impurity 1 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.