Xylometazoline Hydrochloride

Name: Xylometazoline Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-024038

About Xylometazoline Hydrochloride

Listed under CAS 1218-35-5, Xylometazoline Hydrochloride is an impurity of Oxymetazoline available from Vaqora Chemicals. With the molecular formula C16H25ClN2, it has a molar mass of 280.83 g/mol. Alternative names: Xylometazoline HCl and Neo-Synephrine II.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Oxymetazoline, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Xylometazoline Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Oxymetazoline

View every impurity, metabolite and intermediate we list for Oxymetazoline.

Oxymetazoline impurities

Specifications & identifiers

Chemical identifiers
Product name	Xylometazoline Hydrochloride
Catalogue No.	VQ-024038
CAS Number	1218-35-5
IUPAC name	2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride
Molecular formula	C₁₆H₂₅ClN₂
Molecular weight	280.83 g/mol
Exact mass	280.1706
Grade	Reference Standard
HSN code	38229090
InChIKey	YGWFCQYETHJKNX-UHFFFAOYSA-N
SMILES	CC1=CC(=CC(=C1CC2=NCCN2)C)C(C)(C)C.Cl
PubChem CID	5282386

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 1
TPSA	24.4 Å²
Synonyms	Xylometazoline HCl, Neo-Synephrine II, Otrivin hydrochloride, 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline monohydrochloride, Xylomet hcl, Nazo-mist, Otrivine hay fever for, Sinosil Nasal Decongestant, Otrivine, 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride, 2-(4-(tert-butyl)-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazole hydrochloride

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Xylometazoline Hydrochloride?

The CAS Registry Number of Xylometazoline Hydrochloride is 1218-35-5. It is also known as Xylometazoline HCl, Neo-Synephrine II, Otrivin hydrochloride.

What is the molecular formula and molecular weight of Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride has the molecular formula C16H25ClN2 and a molecular weight of 280.83 g/mol.

What is Xylometazoline Hydrochloride used for?

Xylometazoline Hydrochloride is supplied as a characterised reference material related to Oxymetazoline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Xylometazoline Hydrochloride can I order?

We supply Xylometazoline Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Xylometazoline Hydrochloride?

Yes. Every lot of Xylometazoline Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Xylometazoline Hydrochloride be shipped internationally?

Yes. Xylometazoline Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.