2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxa… 1002726-59-1

Name: 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Brand: Vaqora Chemicals
SKU: VQ-048470

About 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Vaqora Chemicals supplies 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one, an impurity of Fostamatinib registered under CAS number 1002726-59-1. The compound has the formula C9H9N3O4, corresponding to a molecular weight of 223.19 g/mol. Systematically, it is named 2,2-dimethyl-6-nitro-4H-pyrido[3,2-b][1,4]oxazin-3-one. It is also known as zine-3(4H)-one.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Fostamatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fostamatinib

View every impurity, metabolite and intermediate we list for Fostamatinib.

Fostamatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Catalogue No.	VQ-048470
CAS Number	1002726-59-1
IUPAC name	2,2-dimethyl-6-nitro-4H-pyrido[3,2-b][1,4]oxazin-3-one
Molecular formula	C₉H₉N₃O₄
Molecular weight	223.19 g/mol
Exact mass	223.0593
Grade	Reference Standard
HSN code	38229090
InChIKey	QPNDHHGIJAMRMD-UHFFFAOYSA-N
SMILES	CC1(C(=O)NC2=C(O1)C=CC(=N2)[N+](=O)[O-])C
PubChem CID	45480401

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	1 / 5
TPSA	97 Å²
Synonyms	2,2-dimethyl-6-nitro-2H,3H,4H-pyrido(3,2-b)(1,4)oxazin-3-one, 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 2,2-dimethyl-6-nitro-, 2,2-Dimethyl-6-nitro-2H,3H,4H-pyrido-[3,2-b][1,4]oxazin-3-one, zine-3(4H)-one, 2,2-dimethyl-6-nitro-2H-pyrido[3,2-B][1,4]oxa-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one?

The CAS Registry Number of 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is 1002726-59-1. It is also known as 2,2-dimethyl-6-nitro-2H,3H,4H-pyrido(3,2-b)(1,4)oxazin-3-one, 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 2,2-dimethyl-6-nitro-, 2,2-Dimethyl-6-nitro-2H,3H,4H-pyrido-[3,2-b][1,4]oxazin-3-one.

What is the molecular formula and molecular weight of 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one?

2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one has the molecular formula C9H9N3O4 and a molecular weight of 223.19 g/mol. Its IUPAC name is 2,2-dimethyl-6-nitro-4H-pyrido[3,2-b][1,4]oxazin-3-one.

What is 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one used for?

2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is supplied as a characterised reference material related to Fostamatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one can I order?

We supply 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one?

Yes. Every lot of 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one be shipped internationally?

Yes. 2,2-Dimethyl-6-nitro-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.