2-Hydroxy-3-methylpyridine

About 2-Hydroxy-3-methylpyridine

2-Hydroxy-3-methylpyridine is a metabolite or degradation product of Pirfenidone carrying the CAS registry number 1003-56-1. With the molecular formula C6H7NO, it has a molar mass of 109.13 g/mol. Its systematic (IUPAC) name is 3-methyl-1H-pyridin-2-one. Alternative names: 3-Methyl-2-pyridone and 3-methylpyridin-2-ol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Pirfenidone, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 2-Hydroxy-3-methylpyridine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Pirfenidone

View every impurity, metabolite and intermediate we list for Pirfenidone.

Pirfenidone impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Hydroxy-3-methylpyridine
Catalogue No.	VQ-032653
CAS Number	1003-56-1
IUPAC name	3-methyl-1H-pyridin-2-one
Molecular formula	C₆H₇NO
Molecular weight	109.13 g/mol
Exact mass	109.0528
Grade	Reference Standard
HSN code	38229090
InChIKey	MVKDNXIKAWKCCS-UHFFFAOYSA-N
SMILES	CC1=CC=CNC1=O
PubChem CID	70481

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²
Synonyms	3-Methyl-2-pyridone, 3-methylpyridin-2-ol, 3-methylpyridin-2(1H)-one, 2(1H)-Pyridinone, 3-methyl-, 3-Methyl-2-pyridinol, 3-Methyl-2-pyridinone, 3-methyl-2-hydroxypyridine, 3-methyl-1,2-dihydropyridin-2-one, 3-Methyl-2(1H)-pyridinone, 2(1H)-Pyridone, 3-methyl-, 3-methylhydropyridin-2-one

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Hydroxy-3-methylpyridine?

The CAS Registry Number of 2-Hydroxy-3-methylpyridine is 1003-56-1. It is also known as 3-Methyl-2-pyridone, 3-methylpyridin-2-ol, 3-methylpyridin-2(1H)-one.

What is the molecular formula and molecular weight of 2-Hydroxy-3-methylpyridine?

2-Hydroxy-3-methylpyridine has the molecular formula C6H7NO and a molecular weight of 109.13 g/mol. Its IUPAC name is 3-methyl-1H-pyridin-2-one.

What is 2-Hydroxy-3-methylpyridine used for?

2-Hydroxy-3-methylpyridine is supplied as a characterised reference material related to Pirfenidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxy-3-methylpyridine can I order?

We supply 2-Hydroxy-3-methylpyridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxy-3-methylpyridine?

Yes. Every lot of 2-Hydroxy-3-methylpyridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxy-3-methylpyridine be shipped internationally?

Yes. 2-Hydroxy-3-methylpyridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.