(3R,4R)-N-Methyl Paroxol

Name: (3R,4R)-N-Methyl Paroxol
Brand: Vaqora Chemicals
SKU: VQ-043250

About (3R,4R)-N-Methyl Paroxol

(3R,4R)-N-Methyl Paroxol (CAS 100332-12-5) is an impurity of Paroxetine offered by Vaqora Chemicals. Formula C13H18FNO, molecular weight 223.29 g/mol. The IUPAC name is [(3R,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl]methanol. Common synonyms include (3R,4R)-Paroxol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

This Paroxetine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Paroxetine

View every impurity, metabolite and intermediate we list for Paroxetine.

Paroxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	(3R,4R)-N-Methyl Paroxol
Catalogue No.	VQ-043250
CAS Number	100332-12-5
IUPAC name	[(3R,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl]methanol
Molecular formula	C₁₃H₁₈FNO
Molecular weight	223.29 g/mol
Exact mass	223.1372
Grade	Reference Standard
HSN code	38229090
InChIKey	CXRHUYYZISIIMT-YPMHNXCESA-N
SMILES	CN1CC[C@H]([C@H](C1)CO)C2=CC=C(C=C2)F
PubChem CID	13608108

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 3
TPSA	23.5 Å²
Synonyms	(3R,4R)-Paroxol, 3-Piperidinemethanol, 4-(4-fluorophenyl)-1-methyl-, (3R,4R)-, rac cis-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol, ((3R,4R)-4-(4-Fluorophenyl)-1-methylpiperidin-3-yl)methanol, cis-(+)-(3R,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P354 + P338, P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (3R,4R)-N-Methyl Paroxol?

The CAS Registry Number of (3R,4R)-N-Methyl Paroxol is 100332-12-5. It is also known as (3R,4R)-Paroxol, 3-Piperidinemethanol, 4-(4-fluorophenyl)-1-methyl-, (3R,4R)-, rac cis-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol.

What is the molecular formula and molecular weight of (3R,4R)-N-Methyl Paroxol?

(3R,4R)-N-Methyl Paroxol has the molecular formula C13H18FNO and a molecular weight of 223.29 g/mol. Its IUPAC name is [(3R,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl]methanol.

What is (3R,4R)-N-Methyl Paroxol used for?

(3R,4R)-N-Methyl Paroxol is supplied as a characterised reference material related to Paroxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (3R,4R)-N-Methyl Paroxol can I order?

We supply (3R,4R)-N-Methyl Paroxol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (3R,4R)-N-Methyl Paroxol?

Yes. Every lot of (3R,4R)-N-Methyl Paroxol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (3R,4R)-N-Methyl Paroxol be shipped internationally?

Yes. (3R,4R)-N-Methyl Paroxol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.