(S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-met… 1004316-93-1

About (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea

(S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea is an impurity of Cobicistat carrying the CAS registry number 1004316-93-1. Its molecular formula is C13H19N3O3S and its molecular weight is 297.38 g/mol. Systematically, it is named 1-methyl-3-[(3S)-2-oxooxolan-3-yl]-1-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]urea. It is also known as EX-A1780.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Cobicistat impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cobicistat

View every impurity, metabolite and intermediate we list for Cobicistat.

Cobicistat impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea
Catalogue No.	VQ-029919
CAS Number	1004316-93-1
IUPAC name	1-methyl-3-[(3S)-2-oxooxolan-3-yl]-1-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]urea
Molecular formula	C₁₃H₁₉N₃O₃S
Molecular weight	297.38 g/mol
Exact mass	297.1147
Grade	Reference Standard
HSN code	38229090
InChIKey	CCSVVYNNTWRTHI-JTQLQIEISA-N
SMILES	CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@H]2CCOC2=O
PubChem CID	59721337

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 5
TPSA	99.8 Å²
Synonyms	(S)-1-[(2-Isopropyl-4-thiazolyl)methyl]-1-methyl-3-(2-oxo-3-tetrahydrofuranyl)urea, (S)-1-((2-Isopropyl-4-thiazolyl)methyl)-1-methyl-3-(2-oxo-3-tetrahydrofuranyl)urea, 3-methyl-1-[(3S)-2-oxooxolan-3-yl]-3-{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}urea, EX-A1780, N-Methyl-N'-[(3S)-2-oxooxolan-3-yl]-N-{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}urea

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea?

The CAS Registry Number of (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea is 1004316-93-1. It is also known as (S)-1-[(2-Isopropyl-4-thiazolyl)methyl]-1-methyl-3-(2-oxo-3-tetrahydrofuranyl)urea, (S)-1-((2-Isopropyl-4-thiazolyl)methyl)-1-methyl-3-(2-oxo-3-tetrahydrofuranyl)urea, 3-methyl-1-[(3S)-2-oxooxolan-3-yl]-3-{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}urea.

What is the molecular formula and molecular weight of (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea?

(S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea has the molecular formula C13H19N3O3S and a molecular weight of 297.38 g/mol. Its IUPAC name is 1-methyl-3-[(3S)-2-oxooxolan-3-yl]-1-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]urea.

What is (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea used for?

(S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea is supplied as a characterised reference material related to Cobicistat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea can I order?

We supply (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea?

Yes. Every lot of (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea be shipped internationally?

Yes. We export (S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.