N-Boc-L-homophenylalanine

Name: N-Boc-L-homophenylalanine
Brand: Vaqora Chemicals
SKU: VQ-043658

About N-Boc-L-homophenylalanine

N-Boc-L-homophenylalanine (CAS 100564-78-1) is an impurity of Carfilzomib offered by Vaqora Chemicals. The compound has the formula C15H21NO4, corresponding to a molecular weight of 279.33 g/mol. The IUPAC name is (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid. Alternative names: Boc-L-homophenylalanine and Boc-Homophe-OH.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Carfilzomib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Boc-L-homophenylalanine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Carfilzomib

View every impurity, metabolite and intermediate we list for Carfilzomib.

Carfilzomib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Boc-L-homophenylalanine
Catalogue No.	VQ-043658
CAS Number	100564-78-1
IUPAC name	(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid
Molecular formula	C₁₅H₂₁NO₄
Molecular weight	279.33 g/mol
Exact mass	279.1471
Grade	Reference Standard
HSN code	38229090
InChIKey	MCODLPJUFHPVQP-LBPRGKRZSA-N
SMILES	CC(C)(C)OC(=O)N[C@@H](CCC1=CC=CC=C1)C(=O)O
PubChem CID	7018726

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²
Synonyms	(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-phenylbutanoic acid, (2S)-2-(((tert-butoxy)carbonyl)amino)-4-phenylbutanoic acid, Boc-L-homophenylalanine, Boc-Homophe-OH, (S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoic acid, Boc-L-Homophe, Boc-homophenylalanine, Boc-L-Homo-Phe, (2S)-2-(tert-butoxycarbonylamino)-4-phenyl-butanoic acid, Benzenebutanoic acid, alpha-[[(1,1-dimethylethoxy)carbonyl]amino]-, (alphaS)-, (2S)-2-[(tert-butoxycarbonyl)amino]-4-phenylbutanoic acid, N-Boc-Homophenylalanine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Boc-L-homophenylalanine?

The CAS Registry Number of N-Boc-L-homophenylalanine is 100564-78-1. It is also known as (2S)-2-{[(tert-butoxy)carbonyl]amino}-4-phenylbutanoic acid, (2S)-2-(((tert-butoxy)carbonyl)amino)-4-phenylbutanoic acid, Boc-L-homophenylalanine.

What is the molecular formula and molecular weight of N-Boc-L-homophenylalanine?

N-Boc-L-homophenylalanine has the molecular formula C15H21NO4 and a molecular weight of 279.33 g/mol. Its IUPAC name is (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid.

What is N-Boc-L-homophenylalanine used for?

N-Boc-L-homophenylalanine is supplied as a characterised reference material related to Carfilzomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Boc-L-homophenylalanine can I order?

We supply N-Boc-L-homophenylalanine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Boc-L-homophenylalanine?

Yes. Every lot of N-Boc-L-homophenylalanine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Boc-L-homophenylalanine be shipped internationally?

Yes. N-Boc-L-homophenylalanine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.