(R)-Ofloxacin

About (R)-Ofloxacin

(R)-Ofloxacin is an impurity of Levofloxacin carrying the CAS registry number 100986-86-5. Its molecular formula is C18H20FN3O4 and its molecular weight is 361.4 g/mol. Alternative names: Ofloxacin R-Isomer and D-Ofloxacin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Levofloxacin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (R)-Ofloxacin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Levofloxacin

View every impurity, metabolite and intermediate we list for Levofloxacin.

Levofloxacin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Ofloxacin
Catalogue No.	VQ-022969
CAS Number	100986-86-5
IUPAC name	(2R)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Molecular formula	C₁₈H₂₀FN₃O₄
Molecular weight	361.4 g/mol
Exact mass	361.1438
Grade	Reference Standard
HSN code	38229090
InChIKey	GSDSWSVVBLHKDQ-SNVBAGLBSA-N
SMILES	C[C@@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
PubChem CID	452723

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	1 / 8
TPSA	73.3 Å²
Synonyms	Ofloxacin R-Isomer, D-Ofloxacin, d-Levofloxacin, (+)-Ofloxacin, Ofloxacin, D-, Dextrofloxacin, d-isomer of ofloxacin

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Ofloxacin?

The CAS Registry Number of (R)-Ofloxacin is 100986-86-5. It is also known as Ofloxacin R-Isomer, D-Ofloxacin, d-Levofloxacin.

What is the molecular formula and molecular weight of (R)-Ofloxacin?

(R)-Ofloxacin has the molecular formula C18H20FN3O4 and a molecular weight of 361.4 g/mol. Its IUPAC name is (2R)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid.

What is (R)-Ofloxacin used for?

(R)-Ofloxacin is supplied as a characterised reference material related to Levofloxacin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Ofloxacin can I order?

We supply (R)-Ofloxacin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Ofloxacin?

Yes. Every lot of (R)-Ofloxacin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Ofloxacin be shipped internationally?

Yes. We export (R)-Ofloxacin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.