Decitabine Related Compound B

About Decitabine Related Compound B

Decitabine Related Compound B is an impurity of Decitabine carrying the CAS registry number 1034301-08-0. With the molecular formula C22H18Cl2N4O6, it has a molar mass of 505.3 g/mol. The IUPAC name is [(2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate. Alternative names: β-Decitabine-3',5'-bis(4-chlorobenzoate) and Decitabine Intermediate CR.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Decitabine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Decitabine Related Compound B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Decitabine

View every impurity, metabolite and intermediate we list for Decitabine.

Decitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	Decitabine Related Compound B
Catalogue No.	VQ-022320
CAS Number	1034301-08-0
IUPAC name	[(2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate
Molecular formula	C₂₂H₁₈Cl₂N₄O₆
Molecular weight	505.3 g/mol
Exact mass	504.0603
Grade	Reference Standard
HSN code	38229090
InChIKey	TWEZWUPSUOJPMB-RCCFBDPRSA-N
SMILES	C1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)COC(=O)C3=CC=C(C=C3)Cl)OC(=O)C4=CC=C(C=C4)Cl
PubChem CID	45256853

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	1 / 6
TPSA	133 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Decitabine Related Compound B?

The CAS Registry Number of Decitabine Related Compound B is 1034301-08-0. It is also known as β-Decitabine-3',5'-bis(4-chlorobenzoate), 3',5'-Bis-O-(4-chlorobenzoyl)-2-deoxy-5-azacytosine, Decitabine Intermediate CR.

What is the molecular formula and molecular weight of Decitabine Related Compound B?

Decitabine Related Compound B has the molecular formula C22H18Cl2N4O6 and a molecular weight of 505.3 g/mol. Its IUPAC name is [(2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate.

What is Decitabine Related Compound B used for?

Decitabine Related Compound B is supplied as a characterised reference material related to Decitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Decitabine Related Compound B can I order?

We supply Decitabine Related Compound B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Decitabine Related Compound B?

Yes. Every lot of Decitabine Related Compound B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Decitabine Related Compound B be shipped internationally?

Yes. Decitabine Related Compound B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.