Niraparib

Name: Niraparib
Brand: Vaqora Chemicals
SKU: VQ-007619

About Niraparib

Niraparib (CAS 1038915-60-4) is a high-purity reference standard of Niraparib offered by Vaqora Chemicals. With the molecular formula C19H20N4O, it has a molar mass of 320.4 g/mol. The IUPAC name is 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide. Alternative names: MK-4827 (Niraparib) and Niraparib (USAN).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Niraparib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Niraparib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Niraparib

View every impurity, metabolite and intermediate we list for Niraparib.

Niraparib impurities

Specifications & identifiers

Chemical identifiers
Product name	Niraparib
Catalogue No.	VQ-007619
CAS Number	1038915-60-4
Other CAS	1038915-64-8, 1038915-73-9, 1613220-15-7
IUPAC name	2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide
Molecular formula	C₁₉H₂₀N₄O
Molecular weight	320.4 g/mol
Exact mass	320.1637
Grade	Reference Standard
HSN code	38229090
InChIKey	PCHKPVIQAHNQLW-CQSZACIVSA-N
SMILES	C1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N
PubChem CID	24958200

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 3
TPSA	72.9 Å²
Synonyms	(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, 2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide, 2-{4-[(3s)-piperidin-3-yl]phenyl}-2h-indazole-7-carboxamide, 2-(4-((3S)-piperidin-3-yl)phenyl)indazole-7-carboxamide, MK-4827 (Niraparib), Niraparib (USAN), 2-[4-[(3S)-3-Piperidyl]phenyl]indazole-7-carboxamide, 2H-Indazole-7-carboxamide, 2-[4-(3S)-3-piperidinylphenyl]-, Niraparib (MK-4827), MK 4827 (Base), (S)-2-[4-(Piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide, 3JD

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H340May cause genetic defects
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Niraparib?

The CAS Registry Number of Niraparib is 1038915-60-4. It is also known as (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, 2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide, 2-{4-[(3s)-piperidin-3-yl]phenyl}-2h-indazole-7-carboxamide.

What is the molecular formula and molecular weight of Niraparib?

Niraparib has the molecular formula C19H20N4O and a molecular weight of 320.4 g/mol. Its IUPAC name is 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide.

What is Niraparib used for?

Niraparib is supplied as a characterised reference material related to Niraparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Niraparib can I order?

We supply Niraparib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Niraparib?

Yes. Every lot of Niraparib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Niraparib be shipped internationally?

Yes. Niraparib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.