N-Desmethyl Mifepristone

Name: N-Desmethyl Mifepristone
Brand: Vaqora Chemicals
SKU: VQ-024077

About N-Desmethyl Mifepristone

N-Desmethyl Mifepristone (CAS 104004-96-8) is a metabolite or degradation product of Mifepristone offered by Vaqora Chemicals. Formula C28H33NO2, molecular weight 415.6 g/mol. Common synonyms include N-Demethyl Mifepristone and Metapristone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Mifepristone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer N-Desmethyl Mifepristone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Mifepristone

View every impurity, metabolite and intermediate we list for Mifepristone.

Mifepristone impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Mifepristone
Catalogue No.	VQ-024077
CAS Number	104004-96-8
IUPAC name	(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-[4-(methylamino)phenyl]-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₈H₃₃NO₂
Molecular weight	415.6 g/mol
Exact mass	415.2511
Grade	Reference Standard
HSN code	38229090
InChIKey	IBLXOBHABOVXDY-WKWWZUSTSA-N
SMILES	CC#C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)NC)C)O
PubChem CID	10070462

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	2 / 3
TPSA	49.3 Å²
Synonyms	N-Demethyl Mifepristone, Metapristone, Desmethylmifepristone, N-Desmethyl-RU 486, 17beta-Hydroxy-11beta-(4-(methylamino)-phenyl)-17alpha-(1-propinyl)-estra-4,9-dien-3-one, 17beta-Hydroxy-11beta-[4-(methylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one, 17beta-hydroxy-17alpha-propynyl-11beta-(4-N-methylaminophenyl)-estra-4,9-dien-3-one, (11b,17b)-17-Hydroxy-11-[4-(methylamino)phenyl]-17-(1-propyn-1-yl)-estra-4,9-dien-3-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Mifepristone?

The CAS Registry Number of N-Desmethyl Mifepristone is 104004-96-8. It is also known as N-Demethyl Mifepristone, Metapristone, Desmethylmifepristone.

What is the molecular formula and molecular weight of N-Desmethyl Mifepristone?

N-Desmethyl Mifepristone has the molecular formula C28H33NO2 and a molecular weight of 415.6 g/mol. Its IUPAC name is (8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-[4-(methylamino)phenyl]-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one.

What is N-Desmethyl Mifepristone used for?

N-Desmethyl Mifepristone is supplied as a characterised reference material related to Mifepristone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Mifepristone can I order?

We supply N-Desmethyl Mifepristone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Mifepristone?

Yes. Every lot of N-Desmethyl Mifepristone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Mifepristone be shipped internationally?

Yes. N-Desmethyl Mifepristone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.