Chlorodenafil

About Chlorodenafil

Chlorodenafil is an impurity of Sildenafil carrying the CAS registry number 1058653-74-9. With the molecular formula C19H21ClN4O3, it has a molar mass of 388.8 g/mol. The IUPAC name is 5-[5-(2-chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Sildenafil impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sildenafil

View every impurity, metabolite and intermediate we list for Sildenafil.

Sildenafil impurities

Specifications & identifiers

Chemical identifiers
Product name	Chlorodenafil
Catalogue No.	VQ-043586
CAS Number	1058653-74-9
IUPAC name	5-[5-(2-chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one
Molecular formula	C₁₉H₂₁ClN₄O₃
Molecular weight	388.8 g/mol
Exact mass	388.1302
Grade	Reference Standard
HSN code	38229090
InChIKey	UOJGGFDIPKRVTP-UHFFFAOYSA-N
SMILES	CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)C(=O)CCl)OCC)C
PubChem CID	135564533

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 5
TPSA	85.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Chlorodenafil?

The CAS Registry Number of Chlorodenafil is 1058653-74-9.

What is the molecular formula and molecular weight of Chlorodenafil?

Chlorodenafil has the molecular formula C19H21ClN4O3 and a molecular weight of 388.8 g/mol. Its IUPAC name is 5-[5-(2-chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one.

What is Chlorodenafil used for?

Chlorodenafil is supplied as a characterised reference material related to Sildenafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlorodenafil can I order?

We supply Chlorodenafil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlorodenafil?

Yes. Every lot of Chlorodenafil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlorodenafil be shipped internationally?

Yes. We export Chlorodenafil worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.