4-[(4-Methylpiperazin-1-yl)methyl]benzoic aci… 106261-49-8

Name: 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride
Brand: Vaqora Chemicals
SKU: VQ-022834

About 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride (CAS 106261-49-8) is an impurity of Imatinib offered by Vaqora Chemicals. With the molecular formula C13H20Cl2N2O2, it has a molar mass of 307.21 g/mol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Imatinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride
Catalogue No.	VQ-022834
CAS Number	106261-49-8
IUPAC name	4-[(4-methylpiperazin-1-yl)methyl]benzoic acid;dihydrochloride
Molecular formula	C₁₃H₂₀Cl₂N₂O₂
Molecular weight	307.21 g/mol
Exact mass	306.0902
Grade	Reference Standard
HSN code	38229090
InChIKey	ISHROKOWRJDOSN-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)O.Cl.Cl
PubChem CID	10335346

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 4
TPSA	43.8 Å²
Synonyms	4-(4-Methylpiperazinomethyl)benzoic Acid Dihydrochloride, 4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride, 4-((4-Methyl-1-piperazinyl)methyl)-benzoic acid dihydrochloride, 4-((4-Methyl-1-piperazinyl)methyl)benzoic acid dihydrochloride, Benzoic acid, 4-[(4-methyl-1-piperazinyl)methyl]-, dihydrochloride, 4-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride, 4-[(4-methyl-1-piperazinyl)methyl]-, hydrochloride (1:2), 4-(4-methyl-piperazinomethyl)benzoic acid dihydrochloride, 4-(4-methylpiperzin-1-ylmethyl)benzoic acid dihydrochloride, 4-(4-Methyl-1-piperazinylmethyl)benzoic acid dihydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements: P233, P260, P261, P264, P264 + P265, P270, P271, P280, P284, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P342 + P316, P362 + P364, P403, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride?

The CAS Registry Number of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride is 106261-49-8. It is also known as 4-(4-Methylpiperazinomethyl)benzoic Acid Dihydrochloride, 4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride, 4-((4-Methyl-1-piperazinyl)methyl)-benzoic acid dihydrochloride.

What is the molecular formula and molecular weight of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride?

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride has the molecular formula C13H20Cl2N2O2 and a molecular weight of 307.21 g/mol.

What is 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride used for?

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride can I order?

We supply 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride?

Yes. Every lot of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride be shipped internationally?

Yes. 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.