Itraconazole Hydroxy Isobutyltriazolone Impur… 106461-41-0

Name: Itraconazole Hydroxy Isobutyltriazolone Impurity
Brand: Vaqora Chemicals
SKU: VQ-026254

About Itraconazole Hydroxy Isobutyltriazolone Impurity

Vaqora Chemicals supplies Itraconazole Hydroxy Isobutyltriazolone Impurity, a metabolite or degradation product of Itraconazole registered under CAS number 106461-41-0. The compound has the formula C22H27N5O2, corresponding to a molecular weight of 393.5 g/mol. Systematically, it is named 2-butan-2-yl-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol-3-one. Alternative names: Itraconazole 2-Hydroxy Metabolite.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Itraconazole, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Itraconazole Hydroxy Isobutyltriazolone Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Itraconazole

View every impurity, metabolite and intermediate we list for Itraconazole.

Itraconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Itraconazole Hydroxy Isobutyltriazolone Impurity
Catalogue No.	VQ-026254
CAS Number	106461-41-0
IUPAC name	2-butan-2-yl-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
Molecular formula	C₂₂H₂₇N₅O₂
Molecular weight	393.5 g/mol
Exact mass	393.2165
Grade	Reference Standard
HSN code	38229090
InChIKey	FFAQILVGBAELHN-UHFFFAOYSA-N
SMILES	CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)O
PubChem CID	4445081

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 5
TPSA	62.6 Å²
Synonyms	Itraconazole 2-Hydroxy Metabolite, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one, 4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-sec-butyl-1,2,4-triazol-3-one, 4-{4-[4-(4-hydroxyphenyl)piperazinyl]phenyl}-1-(methylpropyl)-1,2,4-triazolin- 5-one, 1-(sec-Butyl)-4-[2-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5(4H)-one

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P273, P319, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Itraconazole Hydroxy Isobutyltriazolone Impurity?

The CAS Registry Number of Itraconazole Hydroxy Isobutyltriazolone Impurity is 106461-41-0. It is also known as Itraconazole 2-Hydroxy Metabolite, 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one, 4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-sec-butyl-1,2,4-triazol-3-one.

What is the molecular formula and molecular weight of Itraconazole Hydroxy Isobutyltriazolone Impurity?

Itraconazole Hydroxy Isobutyltriazolone Impurity has the molecular formula C22H27N5O2 and a molecular weight of 393.5 g/mol. Its IUPAC name is 2-butan-2-yl-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol-3-one.

What is Itraconazole Hydroxy Isobutyltriazolone Impurity used for?

Itraconazole Hydroxy Isobutyltriazolone Impurity is supplied as a characterised reference material related to Itraconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Itraconazole Hydroxy Isobutyltriazolone Impurity can I order?

We supply Itraconazole Hydroxy Isobutyltriazolone Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Itraconazole Hydroxy Isobutyltriazolone Impurity?

Yes. Every lot of Itraconazole Hydroxy Isobutyltriazolone Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Itraconazole Hydroxy Isobutyltriazolone Impurity be shipped internationally?

Yes. Itraconazole Hydroxy Isobutyltriazolone Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.