(+)-9-DeMe-DTBZ

Name: (+)-9-DeMe-DTBZ
Brand: Vaqora Chemicals
SKU: VQ-034162

About (+)-9-DeMe-DTBZ

(+)-9-DeMe-DTBZ (CAS 1065193-59-0) is a metabolite or degradation product of Tetrabenazine offered by Vaqora Chemicals. The compound has the formula C18H27NO3, corresponding to a molecular weight of 305.4 g/mol. The IUPAC name is (2R,3R,11bR)-10-methoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine-2,9-diol. It is also known as (+)-9-O-Desmethyl-a-dihydrotetrabenazine or SD-971.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Tetrabenazine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (+)-9-DeMe-DTBZ is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tetrabenazine

View every impurity, metabolite and intermediate we list for Tetrabenazine.

Tetrabenazine impurities

Specifications & identifiers

Chemical identifiers
Product name	(+)-9-DeMe-DTBZ
Catalogue No.	VQ-034162
CAS Number	1065193-59-0
IUPAC name	(2R,3R,11bR)-10-methoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine-2,9-diol
Molecular formula	C₁₈H₂₇NO₃
Molecular weight	305.4 g/mol
Exact mass	305.1991
Grade	Reference Standard
HSN code	38229090
InChIKey	NNGHNWCGIHBKHE-FVQBIDKESA-N
SMILES	CC(C)C[C@@H]1CN2CCC3=CC(=C(C=C3[C@H]2C[C@H]1O)OC)O
PubChem CID	53487027

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 4
TPSA	52.9 Å²
Synonyms	(+)-9-O-Desmethyl-a-dihydrotetrabenazine, SD-971, 9-o-Desmethyl-alpha-htbz, (+)-9-o-Desmethyl-alpha-htbz, (+/-)-9-o-Desmethyl-alpha-htbz, EX-A8281, 9-o-Desmethyl-alpha-dihydrotetrabenazine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (+)-9-DeMe-DTBZ?

The CAS Registry Number of (+)-9-DeMe-DTBZ is 1065193-59-0. It is also known as (+)-9-O-Desmethyl-a-dihydrotetrabenazine, SD-971, 9-o-Desmethyl-alpha-htbz.

What is the molecular formula and molecular weight of (+)-9-DeMe-DTBZ?

(+)-9-DeMe-DTBZ has the molecular formula C18H27NO3 and a molecular weight of 305.4 g/mol. Its IUPAC name is (2R,3R,11bR)-10-methoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine-2,9-diol.

What is (+)-9-DeMe-DTBZ used for?

(+)-9-DeMe-DTBZ is supplied as a characterised reference material related to Tetrabenazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (+)-9-DeMe-DTBZ can I order?

We supply (+)-9-DeMe-DTBZ in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (+)-9-DeMe-DTBZ?

Yes. Every lot of (+)-9-DeMe-DTBZ is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (+)-9-DeMe-DTBZ be shipped internationally?

Yes. We export (+)-9-DeMe-DTBZ worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.