Etravirine 5-Desbromo 6-Chloro Impurity

Name: Etravirine 5-Desbromo 6-Chloro Impurity
Brand: Vaqora Chemicals
SKU: VQ-004940

About Etravirine 5-Desbromo 6-Chloro Impurity

Etravirine 5-Desbromo 6-Chloro Impurity (CAS 1070377-34-2) is an impurity of Etravirine offered by Vaqora Chemicals, specified at 99% purity. The compound has the formula C20H14ClN5O, corresponding to a molecular weight of 375.8 g/mol. Systematically, it is named 4-[6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile. Alternative names: Etravirine Impurity 2 and Etravirine Impurity N2.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Etravirine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Etravirine 5-Desbromo 6-Chloro Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Etravirine

View every impurity, metabolite and intermediate we list for Etravirine.

Etravirine impurities

Specifications & identifiers

Chemical identifiers
Product name	Etravirine 5-Desbromo 6-Chloro Impurity
Catalogue No.	VQ-004940
CAS Number	1070377-34-2
IUPAC name	4-[6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile
Molecular formula	C₂₀H₁₄ClN₅O
Molecular weight	375.8 g/mol
Exact mass	375.0887
Grade	Reference Standard
Purity / assay	99%
HSN code	38229090
InChIKey	CMORVDDKOVDMDP-UHFFFAOYSA-N
SMILES	CC1=CC(=CC(=C1OC2=CC(=NC(=N2)NC3=CC=C(C=C3)C#N)Cl)C)C#N
PubChem CID	50914946

Physical properties
Physical form	Solid
LogP (XLogP3)	5.1
H-bond donors / acceptors	1 / 6
TPSA	94.6 Å²
Synonyms	Etravirine Impurity 2, 4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile, 4-((6-Chloro-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile, 4-((6-Chloro-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethylbenzonitrile, 4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile, 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile, 4-({6-chloro-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile, Etravirine Impurity N2, 4-[6-Chloro-2-(4-cyano-phenylamino)-pyrimidin-4-yloxy]-3,5-dimethyl-benzonitrile, 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitril, 4-{[6-Chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy}-3,5-dimethylbenzonitrile

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Etravirine 5-Desbromo 6-Chloro Impurity?

The CAS Registry Number of Etravirine 5-Desbromo 6-Chloro Impurity is 1070377-34-2. It is also known as Etravirine Impurity 2, 4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile, 4-((6-Chloro-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile.

What is the molecular formula and molecular weight of Etravirine 5-Desbromo 6-Chloro Impurity?

Etravirine 5-Desbromo 6-Chloro Impurity has the molecular formula C20H14ClN5O and a molecular weight of 375.8 g/mol. Its IUPAC name is 4-[6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile.

What is Etravirine 5-Desbromo 6-Chloro Impurity used for?

Etravirine 5-Desbromo 6-Chloro Impurity is supplied as a characterised reference material related to Etravirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Etravirine 5-Desbromo 6-Chloro Impurity can I order?

We supply Etravirine 5-Desbromo 6-Chloro Impurity in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Etravirine 5-Desbromo 6-Chloro Impurity?

Yes. Every lot of Etravirine 5-Desbromo 6-Chloro Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Etravirine 5-Desbromo 6-Chloro Impurity be shipped internationally?

Yes. We export Etravirine 5-Desbromo 6-Chloro Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.