E-Norgestimate
Synonyms: Dexnorgestrel acetime · (+)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one oxime acetate (ester) · (17alpha)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime · d-13beta-Ethyl-17alpha-ethynyl-17beta-acetoxygon-4-en-3-one oxime
E-Norgestimate (CAS 107382-52-5) – Norgestimate impurity standard. C23H31NO3, MW 369.5. Request a quote: COA, bulk packs and worldwide export.
About E-Norgestimate
E-Norgestimate is an impurity of Norgestimate carrying the CAS registry number 107382-52-5. The compound has the formula C23H31NO3, corresponding to a molecular weight of 369.5 g/mol. Alternative names: Dexnorgestrel acetime and anti-Norgestimate.
The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.
As a characterised impurity of Norgestimate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, E-Norgestimate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Norgestimate.
Norgestimate impuritiesSpecifications & identifiers
| Product name | E-Norgestimate |
|---|---|
| Catalogue No. | VQ-026955 |
| CAS Number | 107382-52-5 |
| IUPAC name | [(3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate |
| Molecular formula | C23H31NO3 |
| Molecular weight | 369.5 g/mol |
| Exact mass | 369.2304 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | KIQQMECNKUGGKA-NMYWJIRASA-N |
| SMILES | CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)OC(=O)C)CCC4=C/C(=N/O)/CC[C@H]34 |
| PubChem CID | 6540478 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 4.1 |
| H-bond donors / acceptors | 1 / 4 |
| TPSA | 58.9 Ų |
| Synonyms | Dexnorgestrel acetime, (+)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one oxime acetate (ester), (17alpha)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime, d-13beta-Ethyl-17alpha-ethynyl-17beta-acetoxygon-4-en-3-one oxime, anti-Norgestimate, Norgestimate, E-, 18,19-Dinorpregn-4-en-20-yn-3-one, 17-(acetyloxy)-13-ethyl-, 3-oxime, (3E,17alpha)-, (3E)-17alpha-ethynyl-3-(hydroxyimino)-18a-homoestr-4-en-17beta-yl acetate, 18,19-Dinorpregn-4-en-20-yn-3-one, 17-(acetyloxy)-13-ethyl-, 3-oxime, (17.alpha.)- |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H302Harmful if swallowedH312Harmful in contact with skinH315Causes skin irritationH319Causes serious eye irritationH332Harmful if inhaledH351Suspected of causing cancerH360May damage fertility or the unborn childH361Suspected of damaging fertility or the unborn childH362May cause harm to breast-fed children
Precautionary statements: P203, P260, P261, P263, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P321, P330, P332 + P317, P337 + P317, P362 + P364, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of E-Norgestimate?
The CAS Registry Number of E-Norgestimate is 107382-52-5. It is also known as Dexnorgestrel acetime, (+)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one oxime acetate (ester), (17alpha)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime.
What is the molecular formula and molecular weight of E-Norgestimate?
E-Norgestimate has the molecular formula C23H31NO3 and a molecular weight of 369.5 g/mol. Its IUPAC name is [(3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate.
What is E-Norgestimate used for?
E-Norgestimate is supplied as a characterised reference material related to Norgestimate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of E-Norgestimate can I order?
We supply E-Norgestimate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with E-Norgestimate?
Yes. Every lot of E-Norgestimate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can E-Norgestimate be shipped internationally?
Yes. E-Norgestimate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about E-Norgestimate
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