N-Demethyl Tepotinib

Name: N-Demethyl Tepotinib
Brand: Vaqora Chemicals
SKU: VQ-034124

About N-Demethyl Tepotinib

Vaqora Chemicals supplies N-Demethyl Tepotinib, a metabolite or degradation product of Tepotinib registered under CAS number 1103506-82-6. Its molecular formula is C28H26N6O2 and its molecular weight is 478.5 g/mol. Systematically, it is named 3-[6-oxo-1-[[3-[5-(piperidin-4-ylmethoxy)pyrimidin-2-yl]phenyl]methyl]pyridazin-3-yl]benzonitrile. Alternative names: Desmethyl tepotinib.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Tepotinib, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tepotinib

View every impurity, metabolite and intermediate we list for Tepotinib.

Tepotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Demethyl Tepotinib
Catalogue No.	VQ-034124
CAS Number	1103506-82-6
IUPAC name	3-[6-oxo-1-[[3-[5-(piperidin-4-ylmethoxy)pyrimidin-2-yl]phenyl]methyl]pyridazin-3-yl]benzonitrile
Molecular formula	C₂₈H₂₆N₆O₂
Molecular weight	478.5 g/mol
Exact mass	478.2117
Grade	Reference Standard
HSN code	38229090
InChIKey	QSAJHBBRHWXBFE-UHFFFAOYSA-N
SMILES	C1CNCCC1COC2=CN=C(N=C2)C3=CC=CC(=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
PubChem CID	46836198

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 7
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Demethyl Tepotinib?

The CAS Registry Number of N-Demethyl Tepotinib is 1103506-82-6. It is also known as Desmethyl tepotinib.

What is the molecular formula and molecular weight of N-Demethyl Tepotinib?

N-Demethyl Tepotinib has the molecular formula C28H26N6O2 and a molecular weight of 478.5 g/mol. Its IUPAC name is 3-[6-oxo-1-[[3-[5-(piperidin-4-ylmethoxy)pyrimidin-2-yl]phenyl]methyl]pyridazin-3-yl]benzonitrile.

What is N-Demethyl Tepotinib used for?

N-Demethyl Tepotinib is supplied as a characterised reference material related to Tepotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Demethyl Tepotinib can I order?

We supply N-Demethyl Tepotinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Demethyl Tepotinib?

Yes. Every lot of N-Demethyl Tepotinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Demethyl Tepotinib be shipped internationally?

Yes. We export N-Demethyl Tepotinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.