rac O-Demethyl Ambrisentan

Name: rac O-Demethyl Ambrisentan
Brand: Vaqora Chemicals
SKU: VQ-029090

About rac O-Demethyl Ambrisentan

Listed under CAS 1106685-85-1, rac O-Demethyl Ambrisentan is a metabolite or degradation product of Ambrisentan available from Vaqora Chemicals. With the molecular formula C21H20N2O4, it has a molar mass of 364.4 g/mol. Its systematic (IUPAC) name is 2-(4,6-dimethylpyrimidin-2-yl)oxy-3-hydroxy-3,3-diphenylpropanoic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Ambrisentan, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer rac O-Demethyl Ambrisentan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ambrisentan

View every impurity, metabolite and intermediate we list for Ambrisentan.

Ambrisentan impurities

Specifications & identifiers

Chemical identifiers
Product name	rac O-Demethyl Ambrisentan
Catalogue No.	VQ-029090
CAS Number	1106685-85-1
IUPAC name	2-(4,6-dimethylpyrimidin-2-yl)oxy-3-hydroxy-3,3-diphenylpropanoic acid
Molecular formula	C₂₁H₂₀N₂O₄
Molecular weight	364.4 g/mol
Exact mass	364.1423
Grade	Reference Standard
HSN code	38229090
InChIKey	RYOVARHODFXRJC-UHFFFAOYSA-N
SMILES	CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C
PubChem CID	25183521

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	2 / 6
TPSA	92.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of rac O-Demethyl Ambrisentan?

The CAS Registry Number of rac O-Demethyl Ambrisentan is 1106685-85-1. It is also known as 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-hydroxy-3,3-diphenylpropanoic acid, 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3-hydroxy-3,3-diphenylpropanoic Acid.

What is the molecular formula and molecular weight of rac O-Demethyl Ambrisentan?

rac O-Demethyl Ambrisentan has the molecular formula C21H20N2O4 and a molecular weight of 364.4 g/mol. Its IUPAC name is 2-(4,6-dimethylpyrimidin-2-yl)oxy-3-hydroxy-3,3-diphenylpropanoic acid.

What is rac O-Demethyl Ambrisentan used for?

rac O-Demethyl Ambrisentan is supplied as a characterised reference material related to Ambrisentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of rac O-Demethyl Ambrisentan can I order?

We supply rac O-Demethyl Ambrisentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with rac O-Demethyl Ambrisentan?

Yes. Every lot of rac O-Demethyl Ambrisentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can rac O-Demethyl Ambrisentan be shipped internationally?

Yes. We export rac O-Demethyl Ambrisentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.