2-[4-(Bromomethyl)phenyl]propionic Acid

About 2-[4-(Bromomethyl)phenyl]propionic Acid

2-[4-(Bromomethyl)phenyl]propionic Acid is an impurity of Loxoprofen carrying the CAS registry number 111128-12-2. With the molecular formula C10H11BrO2, it has a molar mass of 243.1 g/mol. Its systematic (IUPAC) name is 2-[4-(bromomethyl)phenyl]propanoic acid. Common synonyms include 2-(4-(Bromomethyl)phenyl)propanoic acid and 4-(Bromomethyl)hydratropic Acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Loxoprofen impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 2-[4-(Bromomethyl)phenyl]propionic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Loxoprofen

View every impurity, metabolite and intermediate we list for Loxoprofen.

Loxoprofen impurities

Specifications & identifiers

Chemical identifiers
Product name	2-[4-(Bromomethyl)phenyl]propionic Acid
Catalogue No.	VQ-038171
CAS Number	111128-12-2
IUPAC name	2-[4-(bromomethyl)phenyl]propanoic acid
Molecular formula	C₁₀H₁₁BrO₂
Molecular weight	243.1 g/mol
Exact mass	241.9942
Grade	Reference Standard
HSN code	38229090
InChIKey	QQXBRVQJMKBAOZ-UHFFFAOYSA-N
SMILES	CC(C1=CC=C(C=C1)CBr)C(=O)O
PubChem CID	2733978

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	2-(4-(Bromomethyl)phenyl)propanoic acid, 4-(Bromomethyl)hydratropic Acid, Loxoprofen intermediate, 4-(1-Carboxyethyl)benzyl bromide, 2-(4-(Bromomethyl)phenyl)propanoicacid, 2-(4-bromomethylphenyl)-proprionic acid, (RS)-2-(4-(bromomethyl)phenyl)propanoic acid

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements: P260, P264, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-[4-(Bromomethyl)phenyl]propionic Acid?

The CAS Registry Number of 2-[4-(Bromomethyl)phenyl]propionic Acid is 111128-12-2. It is also known as 2-(4-(Bromomethyl)phenyl)propanoic acid, 4-(Bromomethyl)hydratropic Acid, Loxoprofen intermediate.

What is the molecular formula and molecular weight of 2-[4-(Bromomethyl)phenyl]propionic Acid?

2-[4-(Bromomethyl)phenyl]propionic Acid has the molecular formula C10H11BrO2 and a molecular weight of 243.1 g/mol. Its IUPAC name is 2-[4-(bromomethyl)phenyl]propanoic acid.

What is 2-[4-(Bromomethyl)phenyl]propionic Acid used for?

2-[4-(Bromomethyl)phenyl]propionic Acid is supplied as a characterised reference material related to Loxoprofen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-[4-(Bromomethyl)phenyl]propionic Acid can I order?

We supply 2-[4-(Bromomethyl)phenyl]propionic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-[4-(Bromomethyl)phenyl]propionic Acid?

Yes. Every lot of 2-[4-(Bromomethyl)phenyl]propionic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-[4-(Bromomethyl)phenyl]propionic Acid be shipped internationally?

Yes. 2-[4-(Bromomethyl)phenyl]propionic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.