N-Nitrosodiethanolamine

About N-Nitrosodiethanolamine

N-Nitrosodiethanolamine is a nitrosamine impurity standard carrying the CAS registry number 1116-54-7 at a purity of 99%. The compound has the formula C4H10N2O3, corresponding to a molecular weight of 134.13 g/mol. The IUPAC name is N,N-bis(2-hydroxyethyl)nitrous amide. Alternative names: Nitrosobis(2-hydroxyethyl)amine and 2,2'-(Nitrosoimino)bisethanol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Specifications & identifiers

Chemical identifiers
Product name	N-Nitrosodiethanolamine
Catalogue No.	VQ-006997
CAS Number	1116-54-7
IUPAC name	N,N-bis(2-hydroxyethyl)nitrous amide
Molecular formula	C₄H₁₀N₂O₃
Molecular weight	134.13 g/mol
Exact mass	134.0691
Grade	Reference Standard
Purity / assay	99%
HSN code	38229090
InChIKey	YFCDLVPYFMHRQZ-UHFFFAOYSA-N
SMILES	C(CO)N(CCO)N=O
PubChem CID	14223

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.5
H-bond donors / acceptors	2 / 5
TPSA	73.1 Å²
Synonyms	Nitrosobis(2-hydroxyethyl)amine, 2,2'-(Nitrosoimino)bisethanol, Diethanolnitrosamine, N,N-Diethanolnitrosamine, NDELA, Nitrosodiethanolamine, Diethanolnitrosoamine, Nitrosoimino diethanol, N-Nitrosoaminodiethanol, Diaethanolnitrosamin, Ethanol, N-nitrosoiminodi-, N-Nitrosodiaethanolamin

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H350May cause cancer

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitrosodiethanolamine?

The CAS Registry Number of N-Nitrosodiethanolamine is 1116-54-7. It is also known as Nitrosobis(2-hydroxyethyl)amine, 2,2'-(Nitrosoimino)bisethanol, Diethanolnitrosamine.

What is the molecular formula and molecular weight of N-Nitrosodiethanolamine?

N-Nitrosodiethanolamine has the molecular formula C4H10N2O3 and a molecular weight of 134.13 g/mol. Its IUPAC name is N,N-bis(2-hydroxyethyl)nitrous amide.

Which grade and pack sizes of N-Nitrosodiethanolamine can I order?

We supply N-Nitrosodiethanolamine in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitrosodiethanolamine?

Yes. Every lot of N-Nitrosodiethanolamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitrosodiethanolamine be shipped internationally?

Yes. N-Nitrosodiethanolamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.