Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1… 112026-42-3

About Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid

Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid is an impurity of Aztreonam carrying the CAS registry number 112026-42-3. Formula C4H8N2O4S, molecular weight 180.19 g/mol. Its systematic (IUPAC) name is (2S,3S)-3-amino-2-methyl-4-oxoazetidine-1-sulfonic acid. Alternative names: 3-Amino-4-methylmonobactamic acid and 3-AMMA.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Aztreonam to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Aztreonam

View every impurity, metabolite and intermediate we list for Aztreonam.

Aztreonam impurities

Specifications & identifiers

Chemical identifiers
Product name	Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid
Catalogue No.	VQ-035905
CAS Number	112026-42-3
IUPAC name	(2S,3S)-3-amino-2-methyl-4-oxoazetidine-1-sulfonic acid
Molecular formula	C₄H₈N₂O₄S
Molecular weight	180.19 g/mol
Exact mass	180.0205
Grade	Reference Standard
HSN code	38229090
InChIKey	ISUIVWNWEDIHJD-HRFVKAFMSA-N
SMILES	C[C@H]1[C@@H](C(=O)N1S(=O)(=O)O)N
PubChem CID	133361

Physical properties
Physical form	Solid
LogP (XLogP3)	-3.6
H-bond donors / acceptors	2 / 5
TPSA	109 Å²
Synonyms	3-Amino-4-methylmonobactamic acid, 3-AMMA, (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid, (2S,3S)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid, (3S-trans)-3-Amino-4-methyl-2-oxo-1-azetidinesulfonic acid, (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulfonic acid, (2S,3S)-3-amino-2-methyl-4-oxo-azetidine-1-sulfonic acid, (2S,3S)-3-Amino-2-methyl-4-oxoazetidin, (3S,4S)-3-amino-4-methyl-2-oxoazetidinesulfonic acid, (2s,3s)-3-amino-2-methyl-4-oxoazetidine-1-sulfonicacid, 3-Amino-2-methyl-4-oxo-1-azetidinesulfonic acid, (2S,3S)-, 1-Azetidinesulfonic acid, 3-amino-2-methyl-4-oxo-, (2S-trans)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid?

The CAS Registry Number of Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid is 112026-42-3. It is also known as 3-Amino-4-methylmonobactamic acid, 3-AMMA, (2S-trans)-3-Amino-2-methyl-4-oxoazetidine-1-sulphonic acid.

What is the molecular formula and molecular weight of Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid?

Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid has the molecular formula C4H8N2O4S and a molecular weight of 180.19 g/mol. Its IUPAC name is (2S,3S)-3-amino-2-methyl-4-oxoazetidine-1-sulfonic acid.

What is Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid used for?

Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid is supplied as a characterised reference material related to Aztreonam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid can I order?

We supply Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid?

Yes. Every lot of Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid be shipped internationally?

Yes. Rel-(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.