3-Chloro-D-alanine methyl ester hydrochloride 112346-82-4

Name: 3-Chloro-D-alanine methyl ester hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-025116

About 3-Chloro-D-alanine methyl ester hydrochloride

Listed under CAS 112346-82-4, 3-Chloro-D-alanine methyl ester hydrochloride is an impurity of Cycloserine available from Vaqora Chemicals. Formula C4H9Cl2NO2, molecular weight 174.02 g/mol. Common synonyms include methyl (2S)-2-amino-3-c and (S)-Methyl 2-amino-3-chloropropanoate HCl.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Cycloserine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cycloserine

View every impurity, metabolite and intermediate we list for Cycloserine.

Cycloserine impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Chloro-D-alanine methyl ester hydrochloride
Catalogue No.	VQ-025116
CAS Number	112346-82-4
IUPAC name	methyl (2S)-2-amino-3-chloropropanoate;hydrochloride
Molecular formula	C₄H₉Cl₂NO₂
Molecular weight	174.02 g/mol
Exact mass	173.001
Grade	Reference Standard
HSN code	38229090
InChIKey	POPBCSXDEXRDSX-AENDTGMFSA-N
SMILES	COC(=O)[C@@H](CCl)N.Cl
PubChem CID	13050342

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	52.3 Å²
Synonyms	(S)-3-Chloroalanine Methyl Ester Hydrochloride, Cycloserine 3-Chloro-D-alanine methyl ester hydrochloride, (S)-Methyl 2-amino-3-chloropropanoate hydrochloride, Methyl (S)-2-amino-3-chloropropanoate hydrochloride, D-Alanine, 3-chloro-, methyl ester, hydrochloride, (S)-Methyl 2-amino-3-chloropropanoatehydrochloride, methyl (2S)-2-amino-3-c, (S)-Methyl 2-amino-3-chloropropanoate HCl, (S)-Methyl2-amino-3-chloropropanoatehydrochloride, H-D-3-Cl-Ala-OMe inverted exclamation mark currencyHCl, D-Alanine, 3-chloro-, methyl ester, hydrochloride (1:1)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264, P264 + P265, P270, P272, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Chloro-D-alanine methyl ester hydrochloride?

The CAS Registry Number of 3-Chloro-D-alanine methyl ester hydrochloride is 112346-82-4. It is also known as (S)-3-Chloroalanine Methyl Ester Hydrochloride, Cycloserine 3-Chloro-D-alanine methyl ester hydrochloride, (S)-Methyl 2-amino-3-chloropropanoate hydrochloride.

What is the molecular formula and molecular weight of 3-Chloro-D-alanine methyl ester hydrochloride?

3-Chloro-D-alanine methyl ester hydrochloride has the molecular formula C4H9Cl2NO2 and a molecular weight of 174.02 g/mol.

What is 3-Chloro-D-alanine methyl ester hydrochloride used for?

3-Chloro-D-alanine methyl ester hydrochloride is supplied as a characterised reference material related to Cycloserine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Chloro-D-alanine methyl ester hydrochloride can I order?

We supply 3-Chloro-D-alanine methyl ester hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Chloro-D-alanine methyl ester hydrochloride?

Yes. Every lot of 3-Chloro-D-alanine methyl ester hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Chloro-D-alanine methyl ester hydrochloride be shipped internationally?

Yes. 3-Chloro-D-alanine methyl ester hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.