(S)-N-Nitroso Anabasine

Name: (S)-N-Nitroso Anabasine
Brand: Vaqora Chemicals
SKU: VQ-049234

About (S)-N-Nitroso Anabasine

(S)-N-Nitroso Anabasine is a nitrosamine impurity of Nicotine Hemisulfate carrying the CAS registry number 1133-64-8. Formula C10H13N3O, molecular weight 191.23 g/mol. Systematically, it is named 3-[(2S)-1-nitrosopiperidin-2-yl]pyridine. Common synonyms include 1-Nitrosoanabasine and (R,s)-n-nitrosoanabasine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (S)-N-Nitroso Anabasine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Nicotine Hemisulfate

View every impurity, metabolite and intermediate we list for Nicotine Hemisulfate.

Nicotine Hemisulfate impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-N-Nitroso Anabasine
Catalogue No.	VQ-049234
CAS Number	1133-64-8
IUPAC name	3-[(2S)-1-nitrosopiperidin-2-yl]pyridine
Molecular formula	C₁₀H₁₃N₃O
Molecular weight	191.23 g/mol
Exact mass	191.1059
Grade	Reference Standard
HSN code	38229090
InChIKey	BXYPVKMROLGXJI-JTQLQIEISA-N
SMILES	C1CCN([C@@H](C1)C2=CN=CC=C2)N=O
PubChem CID	7069270

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	0 / 4
TPSA	45.6 Å²
Synonyms	1-Nitrosoanabasine, (R,s)-n-nitrosoanabasine, Anabasine, 1-nitroso-, (S)-3-(1-Nitroso-2-piperidinyl)pyridine, (S)-3-(1-Nitrosopiperidin-2-yl)pyridine, Pyridine, 3-(1-nitroso-2-piperidinyl)-, (S)-, N-Nitroso-2-(3'-pyridyl)piperidine, 3-[(2S)-1-nitroso-2-piperidyl]pyridine

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-N-Nitroso Anabasine?

The CAS Registry Number of (S)-N-Nitroso Anabasine is 1133-64-8. It is also known as 1-Nitrosoanabasine, (R,s)-n-nitrosoanabasine, Anabasine, 1-nitroso-.

What is the molecular formula and molecular weight of (S)-N-Nitroso Anabasine?

(S)-N-Nitroso Anabasine has the molecular formula C10H13N3O and a molecular weight of 191.23 g/mol. Its IUPAC name is 3-[(2S)-1-nitrosopiperidin-2-yl]pyridine.

What is (S)-N-Nitroso Anabasine used for?

(S)-N-Nitroso Anabasine is supplied as a characterised reference material related to Nicotine Hemisulfate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-N-Nitroso Anabasine can I order?

We supply (S)-N-Nitroso Anabasine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-N-Nitroso Anabasine?

Yes. Every lot of (S)-N-Nitroso Anabasine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-N-Nitroso Anabasine be shipped internationally?

Yes. (S)-N-Nitroso Anabasine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.