1-Bromo-2-fluoro-4-phenoxybenzene

Name: 1-Bromo-2-fluoro-4-phenoxybenzene
Brand: Vaqora Chemicals
SKU: VQ-051793

About 1-Bromo-2-fluoro-4-phenoxybenzene

1-Bromo-2-fluoro-4-phenoxybenzene (CAS 1138557-58-0) is a process intermediate or related compound of Rilzabrutinib offered by Vaqora Chemicals. Its molecular formula is C12H8BrFO and its molecular weight is 267.09 g/mol. Common synonyms include Benzene, 1-bromo-2-fluoro-4-phenoxy-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Rilzabrutinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Bromo-2-fluoro-4-phenoxybenzene in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Rilzabrutinib

View every impurity, metabolite and intermediate we list for Rilzabrutinib.

Rilzabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Bromo-2-fluoro-4-phenoxybenzene
Catalogue No.	VQ-051793
CAS Number	1138557-58-0
IUPAC name	1-bromo-2-fluoro-4-phenoxybenzene
Molecular formula	C₁₂H₈BrFO
Molecular weight	267.09 g/mol
Exact mass	265.9743
InChIKey	LCDBXDWQVNJFPO-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)OC2=CC(=C(C=C2)Br)F
PubChem CID	70085974

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	0 / 2
TPSA	9.2 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Bromo-2-fluoro-4-phenoxybenzene?

The CAS Registry Number of 1-Bromo-2-fluoro-4-phenoxybenzene is 1138557-58-0. It is also known as Benzene, 1-bromo-2-fluoro-4-phenoxy-.

What is the molecular formula and molecular weight of 1-Bromo-2-fluoro-4-phenoxybenzene?

1-Bromo-2-fluoro-4-phenoxybenzene has the molecular formula C12H8BrFO and a molecular weight of 267.09 g/mol. Its IUPAC name is 1-bromo-2-fluoro-4-phenoxybenzene.

What is 1-Bromo-2-fluoro-4-phenoxybenzene used for?

1-Bromo-2-fluoro-4-phenoxybenzene is supplied as a characterised reference material related to Rilzabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Bromo-2-fluoro-4-phenoxybenzene can I order?

We supply 1-Bromo-2-fluoro-4-phenoxybenzene, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Bromo-2-fluoro-4-phenoxybenzene?

Yes. Every lot of 1-Bromo-2-fluoro-4-phenoxybenzene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Bromo-2-fluoro-4-phenoxybenzene be shipped internationally?

Yes. 1-Bromo-2-fluoro-4-phenoxybenzene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.