Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan

About Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan

Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan is an impurity of Losartan carrying the CAS registry number 114772-55-3. The compound has the formula C22H22ClN3O, corresponding to a molecular weight of 379.9 g/mol. Systematically, it is named 2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Losartan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Losartan

View every impurity, metabolite and intermediate we list for Losartan.

Losartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan
Catalogue No.	VQ-026519
CAS Number	114772-55-3
IUPAC name	2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile
Molecular formula	C₂₂H₂₂ClN₃O
Molecular weight	379.9 g/mol
Exact mass	379.1451
Grade	Reference Standard
HSN code	38229090
InChIKey	FGCNIDUBRIVYBP-UHFFFAOYSA-N
SMILES	CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C#N)CO)Cl
PubChem CID	14425664

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 3
TPSA	61.8 Å²
Synonyms	2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imidazole, 2-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]-5-hydroxymethylimidazole, 4'-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)-, 1-[(2'-cyano-biphenyl-4-yl) methyl]-2-butyl-4-chloro-5-hydroxymethyl-imidazole, 1-[(2'-cyano-biphenyl-4-yl)methyl]-2-butyl-4-chloro-5-hydroxymethyl-imidazole, 1-[(2'-Cyanobiphenyl-4-yl)methyl]-2-butyl-4-chloro-5-hydroxymethylimidazole

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan?

The CAS Registry Number of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan is 114772-55-3. It is also known as 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imidazole, 2-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]-5-hydroxymethylimidazole, 4'-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)-.

What is the molecular formula and molecular weight of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan?

Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan has the molecular formula C22H22ClN3O and a molecular weight of 379.9 g/mol. Its IUPAC name is 2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile.

What is Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan used for?

Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan is supplied as a characterised reference material related to Losartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan can I order?

We supply Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan?

Yes. Every lot of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan be shipped internationally?

Yes. We export Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.