Tezacaftor

Name: Tezacaftor
Brand: Vaqora Chemicals
SKU: VQ-028319

About Tezacaftor

Tezacaftor (CAS 1152311-62-0) is a high-purity reference standard of Tezacaftor offered by Vaqora Chemicals. The compound has the formula C26H27F3N2O6, corresponding to a molecular weight of 520.5 g/mol. It is also known as VX-661 or Tezacaftor (VX-661).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Tezacaftor standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tezacaftor is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tezacaftor

View every impurity, metabolite and intermediate we list for Tezacaftor.

Tezacaftor impurities

Specifications & identifiers

Chemical identifiers
Product name	Tezacaftor
Catalogue No.	VQ-028319
CAS Number	1152311-62-0
IUPAC name	1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
Molecular formula	C₂₆H₂₇F₃N₂O₆
Molecular weight	520.5 g/mol
Exact mass	520.1821
Grade	Reference Standard
HSN code	38229090
InChIKey	MJUVRTYWUMPBTR-MRXNPFEDSA-N
SMILES	CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F
PubChem CID	46199646

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	4 / 9
TPSA	113 Å²
Synonyms	VX-661, Tezacaftor (VX-661), VX 661, EX-A1759, US10022352, Compound 315

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tezacaftor?

The CAS Registry Number of Tezacaftor is 1152311-62-0. It is also known as VX-661, Tezacaftor (VX-661), VX 661.

What is the molecular formula and molecular weight of Tezacaftor?

Tezacaftor has the molecular formula C26H27F3N2O6 and a molecular weight of 520.5 g/mol. Its IUPAC name is 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide.

What is Tezacaftor used for?

Tezacaftor is supplied as a characterised reference material related to Tezacaftor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tezacaftor can I order?

We supply Tezacaftor in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tezacaftor?

Yes. Every lot of Tezacaftor is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tezacaftor be shipped internationally?

Yes. We export Tezacaftor worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.