Celecoxib carboxylic acid methyl ester

About Celecoxib carboxylic acid methyl ester

Celecoxib carboxylic acid methyl ester is an impurity of Celecoxib carrying the CAS registry number 1189893-75-1. With the molecular formula C18H14F3N3O4S, it has a molar mass of 425.4 g/mol. Its systematic (IUPAC) name is methyl 4-[1-(4-sulfamoylphenyl)-3-(trifluoromethyl)pyrazol-5-yl]benzoate. Common synonyms include Celecoxib Methyl Ester and Celebrex Carboxylic Acid Methyl Ester.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Celecoxib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Celecoxib

View every impurity, metabolite and intermediate we list for Celecoxib.

Celecoxib impurities

Specifications & identifiers

Chemical identifiers
Product name	Celecoxib carboxylic acid methyl ester
Catalogue No.	VQ-043921
CAS Number	1189893-75-1
IUPAC name	methyl 4-[1-(4-sulfamoylphenyl)-3-(trifluoromethyl)pyrazol-5-yl]benzoate
Molecular formula	C₁₈H₁₄F₃N₃O₄S
Molecular weight	425.4 g/mol
Exact mass	425.0657
Grade	Reference Standard
HSN code	38229090
InChIKey	AUACEYSPFQLYBF-UHFFFAOYSA-N
SMILES	COC(=O)C1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
PubChem CID	22315646

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 9
TPSA	113 Å²
Synonyms	Celecoxib Methyl Ester, Celebrex Carboxylic Acid Methyl Ester, methyl 4-[2-(4-sulfamoylphenyl)-5-(trifluoromethyl)pyrazol-3-yl]benzoate, Methyl 4-(1-(4-sulfamoylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)benzoate, Methyl 4-[1-(4-sulfamoylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Celecoxib carboxylic acid methyl ester?

The CAS Registry Number of Celecoxib carboxylic acid methyl ester is 1189893-75-1. It is also known as Celecoxib Methyl Ester, Celebrex Carboxylic Acid Methyl Ester, methyl 4-[2-(4-sulfamoylphenyl)-5-(trifluoromethyl)pyrazol-3-yl]benzoate.

What is the molecular formula and molecular weight of Celecoxib carboxylic acid methyl ester?

Celecoxib carboxylic acid methyl ester has the molecular formula C18H14F3N3O4S and a molecular weight of 425.4 g/mol. Its IUPAC name is methyl 4-[1-(4-sulfamoylphenyl)-3-(trifluoromethyl)pyrazol-5-yl]benzoate.

What is Celecoxib carboxylic acid methyl ester used for?

Celecoxib carboxylic acid methyl ester is supplied as a characterised reference material related to Celecoxib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Celecoxib carboxylic acid methyl ester can I order?

We supply Celecoxib carboxylic acid methyl ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Celecoxib carboxylic acid methyl ester?

Yes. Every lot of Celecoxib carboxylic acid methyl ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Celecoxib carboxylic acid methyl ester be shipped internationally?

Yes. We export Celecoxib carboxylic acid methyl ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.