N-(Methoxycarbonyl)-D-tert-leucine

About N-(Methoxycarbonyl)-D-tert-leucine

N-(Methoxycarbonyl)-D-tert-leucine is a process intermediate or related compound of Atazanavir carrying the CAS registry number 1191091-65-2. With the molecular formula C8H15NO4, it has a molar mass of 189.21 g/mol. The IUPAC name is (2R)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid. Common synonyms include N-(Methoxycarbonyl)-3-methyl-D-valine and D-Valine,N-(methoxycarbonyl)-3-methyl-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Atazanavir, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Atazanavir

View every impurity, metabolite and intermediate we list for Atazanavir.

Atazanavir impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(Methoxycarbonyl)-D-tert-leucine
Catalogue No.	VQ-013611
CAS Number	1191091-65-2
IUPAC name	(2R)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
Molecular formula	C₈H₁₅NO₄
Molecular weight	189.21 g/mol
Exact mass	189.1001
Grade	Reference Standard
InChIKey	NWPRXAIYBULIEI-YFKPBYRVSA-N
SMILES	CC(C)(C)[C@H](C(=O)O)NC(=O)OC
PubChem CID	73952500

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²
Synonyms	(R)-2-((Methoxycarbonyl)amino)-3,3-dimethylbutanoic acid, N-(Methoxycarbonyl)-3-methyl-D-valine, (2R)-2-[(Methoxycarbonyl)amino]-3,3-dimethylbutanoic acid, (2R)-2-((methoxycarbonyl)amino)-3,3-dimethylbutanoic acid, D-Valine,N-(methoxycarbonyl)-3-methyl-, D-Valine, N-(methoxycarbonyl)-3-methyl-, (R)-2-((Methoxycarbonyl)amino)-3,3-dimethylbutanoicacid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(Methoxycarbonyl)-D-tert-leucine?

The CAS Registry Number of N-(Methoxycarbonyl)-D-tert-leucine is 1191091-65-2. It is also known as (R)-2-((Methoxycarbonyl)amino)-3,3-dimethylbutanoic acid, N-(Methoxycarbonyl)-3-methyl-D-valine, (2R)-2-[(Methoxycarbonyl)amino]-3,3-dimethylbutanoic acid.

What is the molecular formula and molecular weight of N-(Methoxycarbonyl)-D-tert-leucine?

N-(Methoxycarbonyl)-D-tert-leucine has the molecular formula C8H15NO4 and a molecular weight of 189.21 g/mol. Its IUPAC name is (2R)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid.

What is N-(Methoxycarbonyl)-D-tert-leucine used for?

N-(Methoxycarbonyl)-D-tert-leucine is supplied as a characterised reference material related to Atazanavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(Methoxycarbonyl)-D-tert-leucine can I order?

We supply N-(Methoxycarbonyl)-D-tert-leucine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(Methoxycarbonyl)-D-tert-leucine?

Yes. Every lot of N-(Methoxycarbonyl)-D-tert-leucine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(Methoxycarbonyl)-D-tert-leucine be shipped internationally?

Yes. N-(Methoxycarbonyl)-D-tert-leucine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.