6-Methylthioguanine

Name: 6-Methylthioguanine
Brand: Vaqora Chemicals
SKU: VQ-035616

About 6-Methylthioguanine

Vaqora Chemicals supplies 6-Methylthioguanine, an impurity of Guanine registered under CAS number 1198-47-6. Formula C6H7N5S, molecular weight 181.22 g/mol. The IUPAC name is 6-methylsulfanyl-7H-purin-2-amine. Alternative names: s6-methylthioguanine and 2-Amino-6-methylmercaptopurine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Guanine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6-Methylthioguanine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Guanine

View every impurity, metabolite and intermediate we list for Guanine.

Guanine impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Methylthioguanine
Catalogue No.	VQ-035616
CAS Number	1198-47-6
IUPAC name	6-methylsulfanyl-7H-purin-2-amine
Molecular formula	C₆H₇N₅S
Molecular weight	181.22 g/mol
Exact mass	181.0422
Grade	Reference Standard
HSN code	38229090
InChIKey	YEGKYFQLKYGHAR-UHFFFAOYSA-N
SMILES	CSC1=NC(=NC2=C1NC=N2)N
PubChem CID	70976

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	2 / 5
TPSA	106 Å²
Synonyms	s6-methylthioguanine, 2-Amino-6-methylmercaptopurine, 6-(methylthio)-7H-purin-2-amine, 2-Amino-6-methylthiopurine, 6-(methylsulfanyl)-7H-purin-2-amine, Purine, 2-amino-6-(methylthio)-, 1H-Purin-2-amine, 6-(methylthio)-, 6-(methylsulfanyl)-9H-purin-2-amine, 9H-Purin-2-amine, 6-(methylthio)-, S6-Methyl-6-thioguanine, 6-(Methylthio)-1H-purin-2-amine, thioguanine S-methylether

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Methylthioguanine?

The CAS Registry Number of 6-Methylthioguanine is 1198-47-6. It is also known as s6-methylthioguanine, 2-Amino-6-methylmercaptopurine, 6-(methylthio)-7H-purin-2-amine.

What is the molecular formula and molecular weight of 6-Methylthioguanine?

6-Methylthioguanine has the molecular formula C6H7N5S and a molecular weight of 181.22 g/mol. Its IUPAC name is 6-methylsulfanyl-7H-purin-2-amine.

What is 6-Methylthioguanine used for?

6-Methylthioguanine is supplied as a characterised reference material related to Guanine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Methylthioguanine can I order?

We supply 6-Methylthioguanine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Methylthioguanine?

Yes. Every lot of 6-Methylthioguanine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Methylthioguanine be shipped internationally?

Yes. 6-Methylthioguanine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.