2-Hydroxy-2-(4-hydroxyphenyl)acetic acid

Name: 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid
Brand: Vaqora Chemicals
SKU: VQ-029239

About 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid

2-Hydroxy-2-(4-hydroxyphenyl)acetic acid is a metabolite or degradation product of Atenolol carrying the CAS registry number 1198-84-1. Formula C8H8O4, molecular weight 168.15 g/mol. Alternative names: 4-Hydroxymandelic acid and 4-Hydroxy-DL-mandelic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Atenolol, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Atenolol

View every impurity, metabolite and intermediate we list for Atenolol.

Atenolol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Hydroxy-2-(4-hydroxyphenyl)acetic acid
Catalogue No.	VQ-029239
CAS Number	1198-84-1
IUPAC name	2-hydroxy-2-(4-hydroxyphenyl)acetic acid
Molecular formula	C₈H₈O₄
Molecular weight	168.15 g/mol
Exact mass	168.0423
Grade	Reference Standard
HSN code	38229090
InChIKey	YHXHKYRQLYQUIH-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(C(=O)O)O)O
PubChem CID	328

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	3 / 4
TPSA	77.8 Å²
Synonyms	4-Hydroxymandelic acid, 4-Hydroxy-DL-mandelic acid, 2-(4-Hydroxyphenyl)-2-hydroxyacetic acid, (RS)-p-Hydroxymandelic acid, alpha,4-Dihydroxybenzeneacetic acid, (+-)-4-Hydroxymandelic acid, 4-HMA, para-hydroxymandelic acid, pisolithin B, 4-Hydroxyphenylglycolic acid, p-Hydroxymandelic acid, DL-4-Hydroxymandelic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid?

The CAS Registry Number of 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid is 1198-84-1. It is also known as 4-Hydroxymandelic acid, 4-Hydroxy-DL-mandelic acid, 2-(4-Hydroxyphenyl)-2-hydroxyacetic acid.

What is the molecular formula and molecular weight of 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid?

2-Hydroxy-2-(4-hydroxyphenyl)acetic acid has the molecular formula C8H8O4 and a molecular weight of 168.15 g/mol. Its IUPAC name is 2-hydroxy-2-(4-hydroxyphenyl)acetic acid.

What is 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid used for?

2-Hydroxy-2-(4-hydroxyphenyl)acetic acid is supplied as a characterised reference material related to Atenolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid can I order?

We supply 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid?

Yes. Every lot of 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid be shipped internationally?

Yes. 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.