2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

Name: 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
Brand: Vaqora Chemicals
SKU: VQ-050029

About 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine (CAS 1201186-54-0) is a process intermediate or related compound of Upadacitinib offered by Vaqora Chemicals. Formula C13H10BrN3O2S, molecular weight 352.21 g/mol. The IUPAC name is 2-bromo-5-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyrazine. Alternative names: 3-Bromo-5-tosyl-5H-pyrrolo(2,3-b)pyrazine and N-Tosyl-5-bromo-4,7-diazaindole.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Upadacitinib, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Upadacitinib

View every impurity, metabolite and intermediate we list for Upadacitinib.

Upadacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
Catalogue No.	VQ-050029
CAS Number	1201186-54-0
IUPAC name	2-bromo-5-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyrazine
Molecular formula	C₁₃H₁₀BrN₃O₂S
Molecular weight	352.21 g/mol
Exact mass	350.9677
HSN code	2933
InChIKey	UMZKBENCNNDLRF-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)N2C=CC3=NC(=CN=C32)Br
PubChem CID	52987643

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 4
TPSA	73.2 Å²
Synonyms	3-Bromo-5-tosyl-5H-pyrrolo(2,3-b)pyrazine, 2-Bromo-5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazine, 2-Bromo-5-((4-methylphenyl)sulfonyl)-5H-pyrrolo(2,3-b)pyrazine, N-Tosyl-5-bromo-4,7-diazaindole, 5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-5-[(4-methylphenyl)sulfonyl]-, 2-bromo-5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazine, 2-Bromo-5-tosyl-4,7-diazaindole, 2-bromo-5-(p-tolylsulfonyl)pyrrolo[2,3-b]pyrazine, 2-Bromo-5-(toluene-4-sulfonyl)-5H-pyrrolo[2,3-b]pyrazine, 2-Bromo-5-(4-methylphenylsulfonyl)-5H-pyrrolo[2,3-b]pyrazine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine?

The CAS Registry Number of 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine is 1201186-54-0. It is also known as 3-Bromo-5-tosyl-5H-pyrrolo(2,3-b)pyrazine, 2-Bromo-5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazine, 2-Bromo-5-((4-methylphenyl)sulfonyl)-5H-pyrrolo(2,3-b)pyrazine.

What is the molecular formula and molecular weight of 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine?

2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine has the molecular formula C13H10BrN3O2S and a molecular weight of 352.21 g/mol. Its IUPAC name is 2-bromo-5-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyrazine.

What is 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine used for?

2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine is supplied as a characterised reference material related to Upadacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine can I order?

We supply 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine?

Yes. Every lot of 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine be shipped internationally?

Yes. We export 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.