Dorzolamide

Name: Dorzolamide
Brand: Vaqora Chemicals
SKU: VQ-043145

About Dorzolamide

Dorzolamide (CAS 120279-96-1) is a high-purity reference standard of Dorzolamide offered by Vaqora Chemicals. The compound has the formula C10H16N2O4S3, corresponding to a molecular weight of 324.4 g/mol. Its systematic (IUPAC) name is (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide. Alternative names: Dorzolamide (WSM) and 4S,6S-Dorzolamide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Dorzolamide standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Dorzolamide

View every impurity, metabolite and intermediate we list for Dorzolamide.

Dorzolamide impurities

Specifications & identifiers

Chemical identifiers
Product name	Dorzolamide
Catalogue No.	VQ-043145
CAS Number	120279-96-1
IUPAC name	(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
Molecular formula	C₁₀H₁₆N₂O₄S₃
Molecular weight	324.4 g/mol
Exact mass	324.0272
Grade	Reference Standard
HSN code	38229090
InChIKey	IAVUPMFITXYVAF-XPUUQOCRSA-N
SMILES	CCN[C@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C
PubChem CID	5284549

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	2 / 7
TPSA	151 Å²
Synonyms	Dorzolamide (WSM), 4S,6S-Dorzolamide, Dorzolamide, trans-(-)-, 4-ethylamino-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno(5,4-b)thiopyran-2-sulfonamide, 4-ethylamino-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[5,4-b]thiopyran-2-sulfonamide, 4-ethylamino-5,6-dihydro-6-methyl-7,7-dioxide-4H-thieno(2,3-b)thiopyran-2-sulfonamide, 5,6-dihydro-4-ethylamino-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide, Dorzolamide (DZA), 1cil

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dorzolamide?

The CAS Registry Number of Dorzolamide is 120279-96-1. It is also known as Dorzolamide (WSM), 4S,6S-Dorzolamide, Dorzolamide, trans-(-)-.

What is the molecular formula and molecular weight of Dorzolamide?

Dorzolamide has the molecular formula C10H16N2O4S3 and a molecular weight of 324.4 g/mol. Its IUPAC name is (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide.

What is Dorzolamide used for?

Dorzolamide is supplied as a characterised reference material related to Dorzolamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dorzolamide can I order?

We supply Dorzolamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dorzolamide?

Yes. Every lot of Dorzolamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dorzolamide be shipped internationally?

Yes. Dorzolamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.