Delta-1,6-Methylene-17-hydroxyprogesterone 1204325-01-8

About Delta-1,6-Methylene-17-hydroxyprogesterone

Delta-1,6-Methylene-17-hydroxyprogesterone is a metabolite or degradation product of Exemestane carrying the CAS registry number 1204325-01-8. Formula C22H28O3, molecular weight 340.5 g/mol. Common synonyms include Delta-1,6 - Methylene -17-Hydroxyprogest and Delta-1,6-methylene -17-hydroxyprogest.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Exemestane, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Delta-1,6-Methylene-17-hydroxyprogesterone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Exemestane

View every impurity, metabolite and intermediate we list for Exemestane.

Exemestane impurities

Specifications & identifiers

Chemical identifiers
Product name	Delta-1,6-Methylene-17-hydroxyprogesterone
Catalogue No.	VQ-027645
CAS Number	1204325-01-8
IUPAC name	(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₈O₃
Molecular weight	340.5 g/mol
Exact mass	340.2038
Grade	Reference Standard
HSN code	38229090
InChIKey	FOWNNVZRKGYHLF-NWUMPJBXSA-N
SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=C)C4=CC(=O)C=C[C@]34C)C)O
PubChem CID	169441549

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Delta-1,6-Methylene-17-hydroxyprogesterone?

The CAS Registry Number of Delta-1,6-Methylene-17-hydroxyprogesterone is 1204325-01-8. It is also known as Delta-1,6 - Methylene -17-Hydroxyprogest, Delta-1,6-methylene -17-hydroxyprogest, Delta-1,6 -methylene-17-hydroxyprogest.

What is the molecular formula and molecular weight of Delta-1,6-Methylene-17-hydroxyprogesterone?

Delta-1,6-Methylene-17-hydroxyprogesterone has the molecular formula C22H28O3 and a molecular weight of 340.5 g/mol. Its IUPAC name is (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.

What is Delta-1,6-Methylene-17-hydroxyprogesterone used for?

Delta-1,6-Methylene-17-hydroxyprogesterone is supplied as a characterised reference material related to Exemestane. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Delta-1,6-Methylene-17-hydroxyprogesterone can I order?

We supply Delta-1,6-Methylene-17-hydroxyprogesterone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Delta-1,6-Methylene-17-hydroxyprogesterone?

Yes. Every lot of Delta-1,6-Methylene-17-hydroxyprogesterone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Delta-1,6-Methylene-17-hydroxyprogesterone be shipped internationally?

Yes. We export Delta-1,6-Methylene-17-hydroxyprogesterone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.