Filgotinib

Name: Filgotinib
Brand: Vaqora Chemicals
SKU: VQ-037261

About Filgotinib

Vaqora Chemicals supplies Filgotinib, a high-purity reference standard of Filgotinib registered under CAS number 1206161-97-8. Its molecular formula is C21H23N5O3S and its molecular weight is 425.5 g/mol. It is also known as GLPG-0634 or GLPG 0634.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Filgotinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Filgotinib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Filgotinib

View every impurity, metabolite and intermediate we list for Filgotinib.

Filgotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Filgotinib
Catalogue No.	VQ-037261
CAS Number	1206161-97-8
IUPAC name	N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
Molecular formula	C₂₁H₂₃N₅O₃S
Molecular weight	425.5 g/mol
Exact mass	425.1522
Grade	Reference Standard
HSN code	38229090
InChIKey	RIJLVEAXPNLDTC-UHFFFAOYSA-N
SMILES	C1CC1C(=O)NC2=NN3C(=N2)C=CC=C3C4=CC=C(C=C4)CN5CCS(=O)(=O)CC5
PubChem CID	49831257

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 6
TPSA	105 Å²
Synonyms	GLPG-0634, GLPG 0634, Filgotinib (GLPG0634), Filgotinib(GLPG0634), Filgotinib (GLPG-0634), EX-A741

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Filgotinib?

The CAS Registry Number of Filgotinib is 1206161-97-8. It is also known as GLPG-0634, GLPG 0634, Filgotinib (GLPG0634).

What is the molecular formula and molecular weight of Filgotinib?

Filgotinib has the molecular formula C21H23N5O3S and a molecular weight of 425.5 g/mol. Its IUPAC name is N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide.

What is Filgotinib used for?

Filgotinib is supplied as a characterised reference material related to Filgotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Filgotinib can I order?

We supply Filgotinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Filgotinib?

Yes. Every lot of Filgotinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Filgotinib be shipped internationally?

Yes. Filgotinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.