(S)-Cinacalcet Hydrochloride

About (S)-Cinacalcet Hydrochloride

(S)-Cinacalcet Hydrochloride is an impurity of Cinacalcet carrying the CAS registry number 1217809-88-5. Formula C22H23ClF3N, molecular weight 393.9 g/mol. Systematically, it is named N-[(1S)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine. Hydrochloride. It is also known as ent-Cinacalcet Hydrochloride or Cinacalcet Hydrochloride S-Isomer.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Cinacalcet impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cinacalcet

View every impurity, metabolite and intermediate we list for Cinacalcet.

Cinacalcet impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-Cinacalcet Hydrochloride
Catalogue No.	VQ-004277
CAS Number	1217809-88-5
Other CAS	694495-47-1
IUPAC name	N-[(1S)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
Molecular formula	C₂₂H₂₃ClF₃N
Molecular weight	393.9 g/mol
Exact mass	393.1471
Grade	Reference Standard
HSN code	38229090
InChIKey	QANQWUQOEJZMLL-NTISSMGPSA-N
SMILES	C[C@@H](C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
PubChem CID	46781027

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	12 Å²
Synonyms	ent-Cinacalcet Hydrochloride, (S)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride, Cinacalcet Hydrochloride S-Isomer, N-((1S)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)-1-propanamine hydrochloride, N-[(1S)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamine hydrochloride, ent-Cinacalcet HCl, C22H23ClF3N, ent-CinacalcetHydrochloride, CS-M2645, (S)-N-(1-(Naphthalen-1-yl)eth, (S)-a-Methyl-N-[3-[3-(trifluoromethyl)phenyl]p, (S)-N-(1-(phthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264 + P265, P280, P305 + P351 + P338, P319, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-Cinacalcet Hydrochloride?

The CAS Registry Number of (S)-Cinacalcet Hydrochloride is 1217809-88-5. It is also known as ent-Cinacalcet Hydrochloride, (S)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride, Cinacalcet Hydrochloride S-Isomer.

What is the molecular formula and molecular weight of (S)-Cinacalcet Hydrochloride?

(S)-Cinacalcet Hydrochloride has the molecular formula C22H23ClF3N and a molecular weight of 393.9 g/mol.

What is (S)-Cinacalcet Hydrochloride used for?

(S)-Cinacalcet Hydrochloride is supplied as a characterised reference material related to Cinacalcet. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-Cinacalcet Hydrochloride can I order?

We supply (S)-Cinacalcet Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-Cinacalcet Hydrochloride?

Yes. Every lot of (S)-Cinacalcet Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-Cinacalcet Hydrochloride be shipped internationally?

Yes. (S)-Cinacalcet Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.