(2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone 122151-38-6

Name: (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone
Brand: Vaqora Chemicals
SKU: VQ-012751

About (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone

Vaqora Chemicals supplies (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone, a process intermediate or related compound of Posaconazole registered under CAS number 122151-38-6. The compound has the formula C7H13NO2, corresponding to a molecular weight of 143.18 g/mol. Its systematic (IUPAC) name is (2S)-2-hydroxy-1-pyrrolidin-1-ylpropan-1-one. Common synonyms include 1-[(2S)-2-hydroxy-1-oxopropyl]-Pyrrolidine and 1-[(2S-)-2-Hydroxy-1-oxo-proxyl]pyrrolidine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Posaconazole, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Posaconazole

View every impurity, metabolite and intermediate we list for Posaconazole.

Posaconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	(2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone
Catalogue No.	VQ-012751
CAS Number	122151-38-6
IUPAC name	(2S)-2-hydroxy-1-pyrrolidin-1-ylpropan-1-one
Molecular formula	C₇H₁₃NO₂
Molecular weight	143.18 g/mol
Exact mass	143.0946
Grade	Reference Standard
HSN code	2933
InChIKey	KLCGBSXTJWOEJD-LURJTMIESA-N
SMILES	C[C@@H](C(=O)N1CCCC1)O
PubChem CID	11051776

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 2
TPSA	40.5 Å²
Synonyms	1-[(2S)-2-hydroxy-1-oxopropyl]-Pyrrolidine, 1-[(2S-)-2-Hydroxy-1-oxo-proxyl]pyrrolidine, (-)-(S)-N,N-Tetramethylene-2-hydroxypropionamide, (2S)-1-Oxo-1-(1-pyrrolidinyl)-2-propanol, (2S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one, (S)-1-(Pyrrolidin-1-yl)-2-hydroxypropan-1-one, (S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one, 1-Propanone, 2-hydroxy-1-(1-pyrrolidinyl)-, (2S)-, (2S)-2-hydroxy-1-pyrrolidin-1-yl-propan-1-one, Pyrrolidine, 1-[(2S)-2-hydroxy-1-oxopropyl]-, (S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone, Pyrrolidine, 1-[(2S)-2-hydroxy-1-oxopropyl]- (9CI)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone?

The CAS Registry Number of (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone is 122151-38-6. It is also known as 1-[(2S)-2-hydroxy-1-oxopropyl]-Pyrrolidine, 1-[(2S-)-2-Hydroxy-1-oxo-proxyl]pyrrolidine, (-)-(S)-N,N-Tetramethylene-2-hydroxypropionamide.

What is the molecular formula and molecular weight of (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone?

(2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone has the molecular formula C7H13NO2 and a molecular weight of 143.18 g/mol. Its IUPAC name is (2S)-2-hydroxy-1-pyrrolidin-1-ylpropan-1-one.

What is (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone used for?

(2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone is supplied as a characterised reference material related to Posaconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone can I order?

We supply (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone?

Yes. Every lot of (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone be shipped internationally?

Yes. (2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.