5,16-Androstadien-3-ol

About 5,16-Androstadien-3-ol

5,16-Androstadien-3-ol is an impurity of Abiraterone carrying the CAS registry number 1224-94-8. Its molecular formula is C19H28O and its molecular weight is 272.4 g/mol. Its systematic (IUPAC) name is (3S,8S,9S,10R,13R,14S)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol. Common synonyms include Andien-beta and 5,16-androstadien-3 beta-ol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Abiraterone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 5,16-Androstadien-3-ol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Abiraterone

View every impurity, metabolite and intermediate we list for Abiraterone.

Abiraterone impurities

Specifications & identifiers

Chemical identifiers
Product name	5,16-Androstadien-3-ol
Catalogue No.	VQ-028987
CAS Number	1224-94-8
IUPAC name	(3S,8S,9S,10R,13R,14S)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol
Molecular formula	C₁₉H₂₈O
Molecular weight	272.4 g/mol
Exact mass	272.214
Grade	Reference Standard
HSN code	38229090
InChIKey	QVHPTAJAHUONLV-DYKIIFRCSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC=C4[C@@]3(CC[C@@H](C4)O)C
PubChem CID	150900

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	1 / 1
TPSA	20.2 Å²
Synonyms	Andien-beta, 5,16-androstadien-3 beta-ol, androsta-5,16-dien-3 beta-ol, 5,16-Androstadien-3beta-ol, Androsta-5,16-dien-3beta-ol, Androsta-5,16-dien-3-ol, (3beta)-, Androsta-5,16-dien-3-ol, Androsta-5,16-dien-3-ol, (3.beta.)-, Androsta-5,16-Dien-3, A-Ol, 5,16-Androstadien-3.beta.-ol, Androst-5,16-diene-3.beta.ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5,16-Androstadien-3-ol?

The CAS Registry Number of 5,16-Androstadien-3-ol is 1224-94-8. It is also known as Andien-beta, 5,16-androstadien-3 beta-ol, androsta-5,16-dien-3 beta-ol.

What is the molecular formula and molecular weight of 5,16-Androstadien-3-ol?

5,16-Androstadien-3-ol has the molecular formula C19H28O and a molecular weight of 272.4 g/mol. Its IUPAC name is (3S,8S,9S,10R,13R,14S)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol.

What is 5,16-Androstadien-3-ol used for?

5,16-Androstadien-3-ol is supplied as a characterised reference material related to Abiraterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5,16-Androstadien-3-ol can I order?

We supply 5,16-Androstadien-3-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5,16-Androstadien-3-ol?

Yes. Every lot of 5,16-Androstadien-3-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5,16-Androstadien-3-ol be shipped internationally?

Yes. We export 5,16-Androstadien-3-ol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.