Palonosetron 8-Hydroxy 1-Carboxamide

Name: Palonosetron 8-Hydroxy 1-Carboxamide
Brand: Vaqora Chemicals
SKU: VQ-013703

About Palonosetron 8-Hydroxy 1-Carboxamide

Palonosetron 8-Hydroxy 1-Carboxamide (CAS 1227162-74-4) is a process intermediate or related compound of Palonosetron offered by Vaqora Chemicals. The compound has the formula C18H24N2O2, corresponding to a molecular weight of 300.4 g/mol. Systematically, it is named N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-8-hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxamide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Palonosetron, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Specifications & identifiers

Chemical identifiers
Product name	Palonosetron 8-Hydroxy 1-Carboxamide
Catalogue No.	VQ-013703
CAS Number	1227162-74-4
IUPAC name	N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-8-hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxamide
Molecular formula	C₁₈H₂₄N₂O₂
Molecular weight	300.4 g/mol
Exact mass	300.1838
Grade	Reference Standard
HSN code	2933
InChIKey	JFJFGAXBBDZTEE-AAFJCEBUSA-N
SMILES	C1CC(C2=C(C1)C=CC=C2C(=O)N[C@@H]3CN4CCC3CC4)O
PubChem CID	58420448

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	2 / 3
TPSA	52.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Palonosetron 8-Hydroxy 1-Carboxamide?

The CAS Registry Number of Palonosetron 8-Hydroxy 1-Carboxamide is 1227162-74-4. It is also known as 8-Hydroxy-N-((S)-quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide, N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-8-hydroxy-1-naphthalenecarboxamide.

What is the molecular formula and molecular weight of Palonosetron 8-Hydroxy 1-Carboxamide?

Palonosetron 8-Hydroxy 1-Carboxamide has the molecular formula C18H24N2O2 and a molecular weight of 300.4 g/mol. Its IUPAC name is N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-8-hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxamide.

What is Palonosetron 8-Hydroxy 1-Carboxamide used for?

Palonosetron 8-Hydroxy 1-Carboxamide is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Palonosetron 8-Hydroxy 1-Carboxamide can I order?

We supply Palonosetron 8-Hydroxy 1-Carboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Palonosetron 8-Hydroxy 1-Carboxamide?

Yes. Every lot of Palonosetron 8-Hydroxy 1-Carboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Palonosetron 8-Hydroxy 1-Carboxamide be shipped internationally?

Yes. We export Palonosetron 8-Hydroxy 1-Carboxamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.