Tenapanor

Name: Tenapanor
Brand: Vaqora Chemicals
SKU: VQ-042408

About Tenapanor

Listed under CAS 1234423-95-0, Tenapanor is a stable isotope labelled analogue related to Tenapanor available from Vaqora Chemicals. Formula C50H66Cl4N8O10S2, molecular weight 1145.0 g/mol. Common synonyms include Tenapanor-M1 and AZD-1722.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Tenapanor and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tenapanor in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Tenapanor

View every impurity, metabolite and intermediate we list for Tenapanor.

Tenapanor impurities

Specifications & identifiers

Chemical identifiers
Product name	Tenapanor
Catalogue No.	VQ-042408
CAS Number	1234423-95-0
IUPAC name	1-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea
Molecular formula	C₅₀H₆₆Cl₄N₈O₁₀S₂
Molecular weight	1145 g/mol
Exact mass	1144.3068
Grade	Reference Standard
HSN code	38229090
InChIKey	DNHPDWGIXIMXSA-CXNSMIOJSA-N
SMILES	CN1C[C@H](C2=C(C1)C(=CC(=C2)Cl)Cl)C3=CC(=CC=C3)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)C4=CC=CC(=C4)[C@@H]5CN(CC6=C5C=C(C=C6Cl)Cl)C
PubChem CID	71587953

Physical properties
Physical form	Solid
LogP (XLogP3)	5.1
H-bond donors / acceptors	6 / 14
TPSA	235 Å²
Synonyms	Tenapanor-M1, AZD-1722, KHK-7791, Tenapanor free base, AZD 1722, RDX 5791, EX-A2506, US10272079, Compound 002, US10272079, Compound 180

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P319, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tenapanor?

The CAS Registry Number of Tenapanor is 1234423-95-0. It is also known as Tenapanor-M1, AZD-1722, KHK-7791.

What is the molecular formula and molecular weight of Tenapanor?

Tenapanor has the molecular formula C50H66Cl4N8O10S2 and a molecular weight of 1145 g/mol.

What is Tenapanor used for?

Tenapanor is supplied as a characterised reference material related to Tenapanor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tenapanor can I order?

We supply Tenapanor in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tenapanor?

Yes. Every lot of Tenapanor is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tenapanor be shipped internationally?

Yes. Tenapanor is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.