Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Car… 124750-67-0

Name: Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
Brand: Vaqora Chemicals
SKU: VQ-031645

About Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde

Listed under CAS 124750-67-0, Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde is an impurity of Losartan available from Vaqora Chemicals. Formula C22H20ClN3O, molecular weight 377.9 g/mol. Its systematic (IUPAC) name is 2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Losartan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Losartan

View every impurity, metabolite and intermediate we list for Losartan.

Losartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
Catalogue No.	VQ-031645
CAS Number	124750-67-0
IUPAC name	2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile
Molecular formula	C₂₂H₂₀ClN₃O
Molecular weight	377.9 g/mol
Exact mass	377.1295
Grade	Reference Standard
HSN code	38229090
InChIKey	UYWHRPJKNDNURE-UHFFFAOYSA-N
SMILES	CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C#N)C=O)Cl
PubChem CID	23352292

Physical properties
Physical form	Solid
LogP (XLogP3)	5.4
H-bond donors / acceptors	0 / 3
TPSA	58.7 Å²
Synonyms	4`-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-[1,1`-Biphenyl]-2-carbonitrile, 4'-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl][1,1'-biphenyl]-2-carbonitrile, 2-(4-((2-Butyl-4-chloro-5-formylimidazol-1-yl)methyl)phenyl)benzonitrile, 4'-((2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl)(1,1'-biphenyl)-2-carbonitrile, 4'-(2-Butyl-4-chloro-5-formylimidazol-1-ylmethyl)biphenyl-2-carbonitrile, [1,1'-Biphenyl]-2-carbonitrile, 4'-[(2-butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-, 2-butyl-4-chloro-5-formyl-1-(2'-cyanobiphenyl-4-yl)methylimidazole, 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde, 4'-((2-butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264, P264 + P265, P270, P272, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde?

The CAS Registry Number of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde is 124750-67-0. It is also known as 4`-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-[1,1`-Biphenyl]-2-carbonitrile, 4'-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl][1,1'-biphenyl]-2-carbonitrile, 2-(4-((2-Butyl-4-chloro-5-formylimidazol-1-yl)methyl)phenyl)benzonitrile.

What is the molecular formula and molecular weight of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde?

Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde has the molecular formula C22H20ClN3O and a molecular weight of 377.9 g/mol. Its IUPAC name is 2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile.

What is Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde used for?

Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde is supplied as a characterised reference material related to Losartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde can I order?

We supply Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde?

Yes. Every lot of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde be shipped internationally?

Yes. Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.