Losartan Carboxylic Acid

Name: Losartan Carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-031642

About Losartan Carboxylic Acid

Losartan Carboxylic Acid is a metabolite or degradation product of Losartan carrying the CAS registry number 124750-92-1. The compound has the formula C22H21ClN6O2, corresponding to a molecular weight of 436.9 g/mol. Systematically, it is named 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid. Alternative names: EXP-3174 and EXP 3174.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Losartan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Losartan Carboxylic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Losartan

View every impurity, metabolite and intermediate we list for Losartan.

Losartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Losartan Carboxylic Acid
Catalogue No.	VQ-031642
CAS Number	124750-92-1
IUPAC name	2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
Molecular formula	C₂₂H₂₁ClN₆O₂
Molecular weight	436.9 g/mol
Exact mass	436.1415
Grade	Reference Standard
HSN code	38229090
InChIKey	ZEUXAIYYDDCIRX-UHFFFAOYSA-N
SMILES	CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)Cl
PubChem CID	108185

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	2 / 6
TPSA	110 Å²
Synonyms	EXP-3174, EXP 3174, Losartan Carboxylic Acid (EXP-3174), 2-Butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5-formic acid, EX-A803, Losartan carboxylic acid [EXP3174]

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P261, P263, P264, P270, P272, P280, P302 + P352, P318, P321, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Losartan Carboxylic Acid?

The CAS Registry Number of Losartan Carboxylic Acid is 124750-92-1. It is also known as EXP-3174, EXP 3174, Losartan Carboxylic Acid (EXP-3174).

What is the molecular formula and molecular weight of Losartan Carboxylic Acid?

Losartan Carboxylic Acid has the molecular formula C22H21ClN6O2 and a molecular weight of 436.9 g/mol. Its IUPAC name is 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid.

What is Losartan Carboxylic Acid used for?

Losartan Carboxylic Acid is supplied as a characterised reference material related to Losartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Losartan Carboxylic Acid can I order?

We supply Losartan Carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Losartan Carboxylic Acid?

Yes. Every lot of Losartan Carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Losartan Carboxylic Acid be shipped internationally?

Yes. Losartan Carboxylic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.